High-throughput genome-wide RNA interference (RNAi) screening is emerging as an
essential tool to assist biologists in understanding complex cellular processes. The large …

Automated cell segmentation and tracking are critical for quantitative analysis of cell cycle
behavior using time-lapse fluorescence microscopy. However, the complex, dynamic cell …

Motivation: Automated identification of cell cycle phases captured via fluorescent microscopy
is very important for understanding cell cycle and for drug discovery. In this article, we …

Background Several algorithms have been proposed for detecting fluorescently labeled
subcellular objects in microscope images. Many of these algorithms have been designed for …

Abstract Background Nanomaterials such as SiO 2 nanoparticles (SiO 2 NP) are finding
increasing applications in the biomedical and biotechnological fields such as disease …

In this paper, compressive sensing based high-speed time-stretch optical microscopy for two-
dimensional (2D) image acquisition is proposed and experimentally demonstrated for the …

High-throughput microscopy is vital for screening applications, where three-dimensional
(3D) cellular models play a key role. However, due to defocus susceptibility, current 3D high …

The evolution of biomedical imaging technology is allowing the digitization of hundreds of
glass slides at once. There are multiple microscope scanners available in the market …

Context-based modeling is an important step in high-performance lossless data
compression. To effectively define and utilize contexts for natural images is, however, a …

Genome-wide, cell-based screens using high-content screening (HCS) techniques and
automated fluorescence microscopy generate thousands of high-content images that …