The spinocerebellar ataxias type 1 (SCA1), 2 (SCA2), 3 (SCA3), 6 (SCA6) and 7 (SCA7) are
genetically defined autosomal dominantly inherited progressive cerebellar ataxias (ADCAs) …

Abstract Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited,
neurodegenerative disease. It can manifest either with a cerebellar syndrome or as …

Spinocerebellar Ataxia Type 2 (SCA2) is caused by expansion of a polyglutamine encoding
triplet repeat in the human ATXN2 gene beyond (CAG) 31. This is thought to mediate toxic …

Background We recently reported that spinocerebellar ataxia type 2 (SCA2) caused familial
parkinsonism in 2 brothers with predominant symptoms of resting tremor, rigidity, and …

Background: Autosomal dominant spinocerebellar ataxia type 2 (SCA2) bears clinical and
neuropathologic similarities to sporadic multisystem atrophy (MSA) or Parkinson disease, in …

We applied voxel-based morphometry, an indirect volumetric technique, to MRI volumes of
patients carrying the spinocerebellar ataxia type 2 mutation to determine patterns of brain …

Introduction–The genetic and clinical profile of autosomal dominant cerebellar ataxias
(ADCA) displays marked geographical and ethnical variability. Materials and methods–We …

Juvenile parkinsonism (JP) describes patients in whom the clinical features of parkinsonism
manifest before 21 years of age. Many reported cases that had a good response to levodopa …

We describe an exceptional spinocerebellar ataxia type 2 (SCA2) phenotype combining
cerebellar ataxia, levodopa‐responsive parkinsonism, and motor neuron symptoms. We …

We report on 2 brothers, Patients 1 and 2, who presented with a similar clinical syndrome
consisting of resting tumor, bradykinesia, rigidity, and dysarthria at the ages of 40 and 43 …