From oxiranes to oligomers: Architectures of US FDA approved pharmaceuticals containing oxygen heterocycles

MD Delost, DT Smith, BJ Anderson… - Journal of Medicinal …, 2018 - ACS Publications
Oxygen heterocycles are the second most common type of heterocycles that appear as
structural components of US Food and Drug Administration (FDA) approved …

Mucormycosis

JM Steinbrink, MH Miceli - Infectious Disease Clinics, 2021 - id.theclinics.com
Invasive mucormycosis is a life-threatening fungal infection that most frequently occurs in
patients with underlying comorbidities impacting immune system function. 1–4 Rhino-orbital …

Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates

BC Doak, B Over, F Giordanetto, J Kihlberg - Chemistry & biology, 2014 - cell.com
The rule of 5 (Ro5) is a set of in silico guidelines applied to drug discovery to prioritize
compounds with an increased likelihood of high oral absorption. It has been influential in …

The biology and chemistry of antifungal agents: a review

MK Kathiravan, AB Salake, AS Chothe… - Bioorganic & medicinal …, 2012 - Elsevier
In recent years their has been an increased use of antifungal agents and has resulted in the
development of resistance to drugs. Currently, use of standard antifungal therapies can be …

[HTML][HTML] Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America

PG Pappas, CA Kauffman, D Andes… - … diseases: an official …, 2009 - ncbi.nlm.nih.gov
Guidelines for the management of patients with invasive candidiasis and mucosal
candidiasis were prepared by an Expert Panel of the Infectious Diseases Society of America …

Histoplasmosis: a clinical and laboratory update

CA Kauffman - Clinical microbiology reviews, 2007 - Am Soc Microbiol
Infection with Histoplasma capsulatum occurs commonly in areas in the Midwestern United
States and Central America, but symptomatic disease requiring medical care is manifest in …

Nosocomial fungal infections: epidemiology, diagnosis, and treatment

J Perlroth, B Choi, B Spellberg - Medical mycology, 2007 - academic.oup.com
Invasive fungal infections are increasingly common in the nosocomial setting. Furthermore,
because risk factors for these infections continue to increase in frequency, it is likely that …

Dental and oral manifestations of COVID-19 related mucormycosis: diagnoses, management strategies and outcomes

OS Janjua, MS Shaikh, MA Fareed, SM Qureshi… - Journal of Fungi, 2021 - mdpi.com
It has been nearly two years since the pandemic caused by the novel coronavirus disease
(COVID-19) has affected the world. Several innovations and discoveries related to COVID …

Mucormycoses

D Farmakiotis, DP Kontoyiannis - Infectious Disease Clinics, 2016 - id.theclinics.com
The term zygomycosis has been commonly used to describe invasive fungal infections (IFI)
by the Zygomycetes, a term formerly used to describe molds with aseptate or pauciseptate …

[HTML][HTML] Current antifungal drugs and immunotherapeutic approaches as promising strategies to treatment of fungal diseases

S Nami, A Aghebati-Maleki, H Morovati… - Biomedicine & …, 2019 - Elsevier
Invasive candidiasis (IC) can affect individuals with various underlying diseases hospitalized
in different parts of hospitals. In recent decades, IC has caused 27–55% mortality in general …