New β-lactamase inhibitors: a therapeutic renaissance in an MDR world

SM Drawz, KM Papp-Wallace… - Antimicrobial agents and …, 2014 - Am Soc Microbiol
As the incidence of Gram-negative bacterial infections for which few effective treatments
remain increases, so does the contribution of drug-hydrolyzing β-lactamase enzymes to this …

[HTML][HTML] Acquired carbapenemases in Gram-negative bacterial pathogens: detection and surveillance issues

V Miriagou, G Cornaglia, M Edelstein, I Galani… - Clinical microbiology …, 2010 - Elsevier
Acquired carbapenemases are emerging resistance determinants in Gram-negative
pathogens, including Enterobacteriaceae, Pseudomonas aeruginosa and other Gram …

Laboratory detection of Enterobacteriaceae that produce carbapenemases

D Doyle, G Peirano, C Lascols, T Lloyd… - Journal of clinical …, 2012 - Am Soc Microbiol
ABSTRACT A study was designed to evaluate the modified Hodge test (MHT), Mastdiscs ID
inhibitor combination disks (MDI), Rosco Diagnostica Neo-Sensitabs (RDS), metallo-β …

Resistance in nonfermenting gram-negative bacteria: multidrug resistance to the maximum

JE McGowan Jr - American journal of infection control, 2006 - Elsevier
Nonfermenting gram-negative bacteria pose a particular difficulty for the healthcare
community because they represent the problem of multidrug resistance to the maximum …

[HTML][HTML] Bacterial diversity and prevalence of antibiotic resistance genes in the oral microbiome

VSM Almeida, J Azevedo, HF Leal, ATL Queiroz… - PLoS …, 2020 - journals.plos.org
Objectives This study aims to describe the oral microbiome diversity and prevalence of
ARGs in periodontal health and disease. Background The human oral cavity harbors a …

Phenotypic detection of carbapenem-susceptible metallo-β-lactamase-producing gram-negative bacilli in the clinical laboratory

C Franklin, L Liolios, AY Peleg - Journal of clinical microbiology, 2006 - Am Soc Microbiol
Rapid detection of metallo-β-lactamase (MBL)-producing gram-negative pathogens is
critical to prevent their widespread dissemination. Thus far, no standardized phenotypic …

Emergence of NDM-1 Metallo-β-Lactamase in Pseudomonas aeruginosa Clinical Isolates from Serbia

B Jovcic, Z Lepsanovic, V Suljagic… - Antimicrobial agents …, 2011 - Am Soc Microbiol
This work reports, for the first time, the presence of New Delhi metallo-β-lactamase 1 (NDM-
1) in Pseudomonas aeruginosa. Moreover, this is the first report of the NDM-1 presence in …

[HTML][HTML] Carbapenemase genes among multidrug resistant gram negative clinical isolates from a tertiary hospital in Mwanza, Tanzania

MF Mushi, SE Mshana, C Imirzalioglu… - BioMed research …, 2014 - hindawi.com
The burden of antimicrobial resistance (AMR) is rapidly growing across antibiotic classes,
with increased detection of isolates resistant to carbapenems. Data on the prevalence of …

[HTML][HTML] Rapid detection of antibiotic resistance by MALDI-TOF mass spectrometry using a novel direct-on-target microdroplet growth assay

EA Idelevich, K Sparbier, M Kostrzewa… - Clinical Microbiology and …, 2018 - Elsevier
Objectives We aimed to develop a universal phenotypic method, which allows easy and
rapid antimicrobial susceptibility testing independently of underlying resistance …

Fosfomycin susceptibility in carbapenem-resistant Enterobacteriaceae from Germany

M Kaase, F Szabados, A Anders… - Journal of Clinical …, 2014 - Am Soc Microbiol
Due to the increase in multidrug-resistant Enterobacteriaceae, the interest in older
antimicrobial agents, like fosfomycin, has increased. In this study, we used agar dilution for …