Preterm labour is the major cause of perinatal morbidity and mortality in humans. The
incidence is around 10% and the causes are often unknown. Consumption of dietary n‐6 …

Placental oestrogens play an important role as local regulators of placental growth and
differentiation during gestation, and toward term they are also involved in the preparation of …

Locally produced estrogens are important paracrine regulators of placental growth and
differentiation in cattle and sheep. The key enzyme of estrogen biosynthesis, aromatase …

Although prostaglandin E 2 (PGE 2) has been identified as a central mediator of the cervical
ripening process, the mechanisms responsible for PGE 2 ripening are still poorly …

Prematurity is one of the leading causes of infant mortality. It may result from intrauterine
infection, which mediates premature labor by stimulating the production of inflammatory lipid …

Objective To compare the safety and effectiveness of vaginal misoprostol with combined
vaginal misoprostol and estradiol for induction of labor in unfavorable cervix. Method A …

Preterm labor is one of the major problems in obstetrics and its incidence has not decreased
since the mid-1980s. There have, however, been considerable advances in our …

An ultra performance liquid chromatography–electrospray ionization-tandem mass
spectrometry (UPLC–MS/MS) method was developed for the analysis of steroids and their …

Contraction of uterus tissue frequently occurs throughout the estrous cycle and is regulated
by several endogenous factors, including estradiol, progesterone, luteinizing hormone …

In the present study, we examined the in vivo effects of estradiol (E 2) and progesterone on
cyclooxygenase (COX) 2, prostaglandin F synthase (PTGFS, also known as PGFS), and …