Gene expression is regulated by many factors, including transcription factors, chromatin
three-dimensional topology, modifications of DNA and histone proteins, and non-coding …

Comprehensive Summary SPONGE (Simulation Package tOward Next GEneration
molecular modeling) is a software package for molecular dynamics (MD) simulation of …

Within the confines of a densely populated cell nucleus, chromatin undergoes intricate
folding, forming loops, domains, and compartments under the governance of topological …

The review analyzes the role of physicochemical processes in the formation of the function-
dependent architecture of the cell nucleus, built on the platform of a folded genome. The …

In this work, we studied the equilibrium structures formed by a single (AB) k multiblock
copolymer chain. Within our model, the interactions between the A-type beads were …