SERS liquid biopsy: An emerging tool for medical diagnosis

V Moisoiu, SD Iancu, A Stefancu, T Moisoiu… - Colloids and Surfaces B …, 2021 - Elsevier
Surface-enhanced Raman scattering (SERS) is emerging as a novel strategy for biofluid
analysis. In this review, we delineate four experimental SERS protocols that are frequently …

[HTML][HTML] Mass spectrometry based proteomics and metabolomics in personalized oncology

T Kowalczyk, M Ciborowski, J Kisluk… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Precision medicine (PM) means the customization of healthcare with decisions and
practices adjusted to the individual patient. It includes personalized diagnostics, patients' …

[HTML][HTML] Specific gut microbiome and serum metabolome changes in lung cancer patients

F Zhao, R An, L Wang, J Shan, X Wang - Frontiers in cellular and …, 2021 - frontiersin.org
Background Lung cancer (LC) is one of the most aggressive, prevalent and fatal
malignancies. Gut microbes and their associated metabolites are thought to cause and …

[HTML][HTML] Hypoxanthine is a checkpoint stress metabolite in colonic epithelial energy modulation and barrier function

JS Lee, RX Wang, EE Alexeev, JM Lanis… - Journal of Biological …, 2018 - ASBMB
Intestinal epithelial cells form a selectively permeable barrier to protect colon tissues from
luminal microbiota and antigens and to mediate nutrient, fluid, and waste flux in the intestinal …

SWATHtoMRM: development of high-coverage targeted metabolomics method using SWATH technology for biomarker discovery

H Zha, Y Cai, Y Yin, Z Wang, K Li, ZJ Zhu - Analytical Chemistry, 2018 - ACS Publications
The complexity of metabolome presents a great analytical challenge for quantitative
metabolite profiling, and restricts the application of metabolomics in biomarker discovery …

Oral bacteriome and mycobiome across stages of oral carcinogenesis

W Heng, W Wang, T Dai, P Jiang, Y Lu, R Li… - Microbiology …, 2022 - Am Soc Microbiol
Oral microbial dysbiosis contributes to the development of oral squamous cell carcinoma
(OSCC). Numerous studies have focused on variations in the oral bacterial microbiota of …

Label‐free diagnosis for colorectal cancer through coffee ring‐assisted surface‐enhanced Raman spectroscopy on blood serum

Y Hong, Y Li, L Huang, W He, S Wang… - Journal of …, 2020 - Wiley Online Library
Surface‐enhanced Raman spectroscopy (SERS) is garnering considerable attention for the
swift diagnosis of pathogens and abnormal biological status, that is, cancers. In this work, a …

Metabolomic profiling identified serum metabolite biomarkers and related metabolic pathways of colorectal cancer

C Zhang, S Zhou, H Chang, F Zhuang, Y Shi… - Disease …, 2021 - Wiley Online Library
Background. The screening and early detection of colorectal cancer (CRC) still remain a
challenge due to the lack of reliable and effective serum biomarkers. Thus, this study is …

Metabolic-dysregulation-based iEESI-MS reveals potential biomarkers associated with early-stage and progressive colorectal cancer

R Zheng, R Su, F Xing, Q Li, B Liu, D Wang… - Analytical …, 2022 - ACS Publications
The application of rapid and accurate diagnostic methods can improve colorectal cancer
(CRC) survival rates dramatically. Here, we used a non-targeted metabolic analysis strategy …

[HTML][HTML] Untargeted metabolomics reveals major differences in the plasma metabolome between colorectal cancer and colorectal adenomas

T Gumpenberger, S Brezina, P Keski-Rahkonen… - Metabolites, 2021 - mdpi.com
Sporadic colorectal cancer is characterized by a multistep progression from normal
epithelium to precancerous low-risk and high-risk adenomas to invasive cancer. Yet, the …