SERS liquid biopsy: An emerging tool for medical diagnosis
Surface-enhanced Raman scattering (SERS) is emerging as a novel strategy for biofluid
analysis. In this review, we delineate four experimental SERS protocols that are frequently …
analysis. In this review, we delineate four experimental SERS protocols that are frequently …
[HTML][HTML] Mass spectrometry based proteomics and metabolomics in personalized oncology
T Kowalczyk, M Ciborowski, J Kisluk… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Precision medicine (PM) means the customization of healthcare with decisions and
practices adjusted to the individual patient. It includes personalized diagnostics, patients' …
practices adjusted to the individual patient. It includes personalized diagnostics, patients' …
[HTML][HTML] Specific gut microbiome and serum metabolome changes in lung cancer patients
F Zhao, R An, L Wang, J Shan, X Wang - Frontiers in cellular and …, 2021 - frontiersin.org
Background Lung cancer (LC) is one of the most aggressive, prevalent and fatal
malignancies. Gut microbes and their associated metabolites are thought to cause and …
malignancies. Gut microbes and their associated metabolites are thought to cause and …
[HTML][HTML] Hypoxanthine is a checkpoint stress metabolite in colonic epithelial energy modulation and barrier function
JS Lee, RX Wang, EE Alexeev, JM Lanis… - Journal of Biological …, 2018 - ASBMB
Intestinal epithelial cells form a selectively permeable barrier to protect colon tissues from
luminal microbiota and antigens and to mediate nutrient, fluid, and waste flux in the intestinal …
luminal microbiota and antigens and to mediate nutrient, fluid, and waste flux in the intestinal …
SWATHtoMRM: development of high-coverage targeted metabolomics method using SWATH technology for biomarker discovery
The complexity of metabolome presents a great analytical challenge for quantitative
metabolite profiling, and restricts the application of metabolomics in biomarker discovery …
metabolite profiling, and restricts the application of metabolomics in biomarker discovery …
Oral bacteriome and mycobiome across stages of oral carcinogenesis
W Heng, W Wang, T Dai, P Jiang, Y Lu, R Li… - Microbiology …, 2022 - Am Soc Microbiol
Oral microbial dysbiosis contributes to the development of oral squamous cell carcinoma
(OSCC). Numerous studies have focused on variations in the oral bacterial microbiota of …
(OSCC). Numerous studies have focused on variations in the oral bacterial microbiota of …
Label‐free diagnosis for colorectal cancer through coffee ring‐assisted surface‐enhanced Raman spectroscopy on blood serum
Surface‐enhanced Raman spectroscopy (SERS) is garnering considerable attention for the
swift diagnosis of pathogens and abnormal biological status, that is, cancers. In this work, a …
swift diagnosis of pathogens and abnormal biological status, that is, cancers. In this work, a …
Metabolomic profiling identified serum metabolite biomarkers and related metabolic pathways of colorectal cancer
C Zhang, S Zhou, H Chang, F Zhuang, Y Shi… - Disease …, 2021 - Wiley Online Library
Background. The screening and early detection of colorectal cancer (CRC) still remain a
challenge due to the lack of reliable and effective serum biomarkers. Thus, this study is …
challenge due to the lack of reliable and effective serum biomarkers. Thus, this study is …
Metabolic-dysregulation-based iEESI-MS reveals potential biomarkers associated with early-stage and progressive colorectal cancer
R Zheng, R Su, F Xing, Q Li, B Liu, D Wang… - Analytical …, 2022 - ACS Publications
The application of rapid and accurate diagnostic methods can improve colorectal cancer
(CRC) survival rates dramatically. Here, we used a non-targeted metabolic analysis strategy …
(CRC) survival rates dramatically. Here, we used a non-targeted metabolic analysis strategy …
[HTML][HTML] Untargeted metabolomics reveals major differences in the plasma metabolome between colorectal cancer and colorectal adenomas
T Gumpenberger, S Brezina, P Keski-Rahkonen… - Metabolites, 2021 - mdpi.com
Sporadic colorectal cancer is characterized by a multistep progression from normal
epithelium to precancerous low-risk and high-risk adenomas to invasive cancer. Yet, the …
epithelium to precancerous low-risk and high-risk adenomas to invasive cancer. Yet, the …