Four rat embryo fibroblast (REF) cell lines with defined oncogenic transformation were used
to study the relationship between tumorigenic conversion, metabolism, and development of …

Early Wound Healing Exhibits Cytokine Surge Without Evidence... : Annals of Surgery Early
Wound Healing Exhibits Cytokine Surge Without Evidence of Hypoxia : Annals of Surgery …

Cancer is a complex, multiscale process, in which genetic mutations occurring at a
subcellular level manifest themselves as functional and morphological changes at the …

The distribution of oxygen, nutrients and metabolic wastes in multicellular tumor spheroids
and its dependence on the parameters characterizing the spheroid (ie, spheroid geometry …

The efficacy of antitumor radiotherapy can be enhanced by utilizing nonradioactive
nanoparticles that emit secondary radiation when activated by a primary beam. They consist …

The culture of EMT6/Ro multicellular tumor spheroids in a 20-fold range of glucose
concentrations and a 4-fold range of oxygen tensions had profound effects on the cell …

Simple Summary Tumor cells have high levels of metabolic activity, which makes the
environment around them more acidic. This acidic environment encourages the …

Introduction: Human pluripotent stem cells (hPSCs) provide many opportunities for
application in regenerative medicine due to their ability to differentiate into cells from all …

The GOX/CAT system: A novel enzymatic method to independently control hydrogen peroxide
and hypoxia in cell culture Page 1 121 ·Advances in Medical Sciences ·Vol. 54(2) · 2009 ·pp …

Recent studies have generated a large amount of data supporting the hypothesis that
hypoxia drives tumor angiogenesis. The relationship between the two is often considered a …