Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

Pancreatic cancer is one of the harshest and most challenging cancers to treat, often labeled
as incurable. Chemotherapy continues to be the most popular treatment yet yields a very …

Targeting tumour immunosuppressive microenvironment is a crucial strategy in
immunotherapy. However, the critical role of the tumour lymph node (LN) immune …

It is urgent to develop more effective mRNA vaccines against the emerging severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) variants owing to the immune escape …

Although toll-like receptor (TLR) agonists hold great promise as immune modulators for
reprogramming the suppressive immune landscape in pancreatic ductal adenocarcinoma …

Immunotherapy has become a promising research “hotspot” in cancer treatment.“Soldier”
immune cells are not uniform throughout the body; they accumulate mostly in the immune …

With the economy's globalization and the population's aging, cancer has become the
leading cause of death in most countries. While imposing a considerable burden on society …

Lung cancer is the major cause of cancer death worldwide. Immune checkpoint inhibitors
(ICIs) of PD-1/PD-L1 have improved the survival rate in some patients with lung cancer …

Despite their immense therapeutic potential, cancer immunotherapies such as immune
checkpoint blockers (ICBs) benefit only a small subset of patients. Toll-like receptor agonists …

RNA sensors detect foreign and endogenous RNAs to protect the host by initiating innate
and adaptive immune response. In tumor microenvironment (TME), activation of RNA …