Systemic therapy often results in the reduction of tumor size but rarely succeeds in
eradicating all cancer cells. Drug efflux, persistence of cancer stem cells (CSCs), epithelial …

Prostate cancer (PC) represents the most diagnosed and the second most lethal cancer in
men worldwide. Its development and progression occur in concert with alterations in the …

Background/Aim: Prostate cancer is one of the most common cancers in men which remains
a global public health issue. Treatment of prostate cancer is becoming increasingly intensive …

Prostate cancer (PCa) is one of the leading causes of cancer-related deaths in men.
Although androgen deprivation therapies (ADT) and antiandrogens confer increased …

Advanced prostate cancer (PCa) represents the fifth cause of cancer death worldwide.
Although survival has improved with second-generation androgen signaling and Parp …

Objective Circular RNA is a type of endogenous RNA molecule with a stable closed-loop
structure which is ubiquitous in mammals. Circular RNA HIPK3 (circHIPK3) is highly …

Background The androgen receptor (AR) remains a critical driver in metastatic castration-
resistant prostate cancer (mCRPC). Profiling AR aberrations in both circulating DNA and …

Simple Summary Advanced prostate cancer remains a clinical challenge, requiring novel
therapeutic treatments and biomarkers for patient-risk stratification. From a metabolic …

Prostate cancer is the most common type of cancer among men and the second most
frequent cause of cancer-related mortality around the world. The progression of advanced …

Background There has been considerable development in the treatment of advanced
prostate cancer over the last decade. A number of agents, including docetaxel, cabazitaxel …