[HTML][HTML] Emerging fungal infections: new patients, new patterns, and new pathogens

DZP Friedman, IS Schwartz - Journal of Fungi, 2019 - mdpi.com
The landscape of clinical mycology is constantly changing. New therapies for malignant and
autoimmune diseases have led to new risk factors for unusual mycoses. Invasive …

[HTML][HTML] Azole-resistant Aspergillus fumigatus in the environment: Identifying key reservoirs and hotspots of antifungal resistance

C Burks, A Darby, L Gómez Londoño… - PLoS …, 2021 - journals.plos.org
Aspergillus fumigatus is an opportunistic human pathogen that causes aspergillosis, a
spectrum of environmentally acquired respiratory illnesses. It has a cosmopolitan distribution …

Trends in agricultural triazole fungicide use in the United States, 1992–2016 and possible implications for antifungal-resistant fungi in human disease

M Toda, KD Beer, KM Kuivila, TM Chiller… - Environmental health …, 2021 - ehp.niehs.nih.gov
Background: The fungus Aspergillus fumigatus (A. fumigatus) is the leading cause of
invasive mold infections, which cause severe disease and death in immunocompromised …

[HTML][HTML] Fungicide effects on human fungal pathogens: cross-resistance to medical drugs and beyond

RW Bastos, L Rossato, GH Goldman… - PLoS Pathogens, 2021 - journals.plos.org
Fungal infections are underestimated threats that affect over 1 billion people, and Candida
spp., Cryptococcus spp., and Aspergillus spp. are the 3 most fatal fungi. The treatment of …

[HTML][HTML] Triazole resistance in Aspergillus fumigatus: recent insights and challenges for patient management

PPA Lestrade, JF Meis, WJG Melchers… - Clinical Microbiology and …, 2019 - Elsevier
Abstract Background Triazole resistance in Aspergillus fumigatus is widespread and
threatens first-line triazole therapy in patients with Aspergillus diseases. Objectives To give …

[HTML][HTML] Race and ethnicity: Risk factors for fungal infections?

JD Jenks, CI Aneke, MM Al-Obaidi, M Egger… - PLoS …, 2023 - journals.plos.org
Racial and ethnic identities, largely understood as social rather than biologic constructs,
may impact risk for acquiring infectious diseases, including fungal infections. Risk factors …

Aspergillus fumigatus and aspergillosis: From basics to clinics

A Arastehfar, A Carvalho, J Houbraken… - Studies in …, 2021 - ingentaconnect.com
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

[HTML][HTML] Molecular mechanisms governing antifungal drug resistance

Y Lee, N Robbins, LE Cowen - npj Antimicrobials and Resistance, 2023 - nature.com
Fungal pathogens are a severe public health problem. The leading causative agents of
systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus …

Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

JM Rybak, W Ge, NP Wiederhold, JE Parker, SL Kelly… - MBio, 2019 - Am Soc Microbiol
Aspergillus fumigatus is the predominant pathogen of invasive aspergillosis, a disease state
credited with over 200,000 life-threatening infections each year. The triazole class of …

Evidence for the agricultural origin of resistance to multiple antimicrobials in Aspergillus fumigatus, a fungal pathogen of humans

SE Kang, LG Sumabat, T Melie, B Mangum, M Momany… - G3, 2022 - academic.oup.com
Pathogen resistance to clinical antimicrobial agents is an urgent problem. The fungus
Aspergillus fumigatus causes 300,000 life-threatening infections in susceptible humans …