[HTML][HTML] MYCT1 in cancer development: Gene structure, regulation, and biological implications for diagnosis and treatment
J Xu, Y Sun, W Fu, S Fu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract Myc target 1 (MYCT1), located at 6q25. 2, is a crucial player in cancer development.
While widely distributed in cells, its subcellular localization varies across different cancer …
While widely distributed in cells, its subcellular localization varies across different cancer …
[HTML][HTML] Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes
MT Teh, E Gemenetzidis, T Chaplin, BD Young… - Molecular cancer, 2010 - Springer
Background The human cell cycle transcription factor FOXM1 is known to play a key role in
regulating timely mitotic progression and accurate chromosomal segregation during cell …
regulating timely mitotic progression and accurate chromosomal segregation during cell …
[HTML][HTML] MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway
PJ Yue, YY Sun, YH Li, ZM Xu, WN Fu - Cellular Signalling, 2020 - Elsevier
MYCT1 has an inhibitory effect on the migration of laryngeal cancer cells, although the
underlying molecular mechanism remains unknown. In this study, we aimed to explore the …
underlying molecular mechanism remains unknown. In this study, we aimed to explore the …
YY 1 directly suppresses MYCT 1 leading to laryngeal tumorigenesis and progress
SY Qu, YY Sun, YH Li, ZM Xu, WN Fu - Cancer medicine, 2017 - Wiley Online Library
YY 1 is a key transcription factor and plays different roles in various cancers. However, role
and mechanism of YY 1 in laryngeal cancer are still unknown. YY 1 and MYCT 1 mRNA and …
and mechanism of YY 1 in laryngeal cancer are still unknown. YY 1 and MYCT 1 mRNA and …
[HTML][HTML] MYCT1-TV, A Novel MYCT1 Transcript, Is Regulated by c-Myc and May Participate in Laryngeal Carcinogenesis
S Fu, Y Guo, H Chen, ZM Xu, GB Qiu, M Zhong… - PLoS …, 2011 - journals.plos.org
Background MYCT1, a putative target of c-Myc, is a novel candidate tumor suppressor gene
cloned from laryngeal squamous cell carcinoma (LSCC). Its transcriptional regulation and …
cloned from laryngeal squamous cell carcinoma (LSCC). Its transcriptional regulation and …
[HTML][HTML] Overexpression of MYCT1 Inhibits Proliferation and Induces Apoptosis in Human Acute Myeloid Leukemia HL-60 and KG-1a Cells in vitro and in vivo
S Fu, Y Fu, F Chen, Y Hu, B Quan… - Frontiers in …, 2018 - frontiersin.org
MYC target 1 (MYCT1), a direct target gene of c-Myc, is a novel candidate tumor suppressor
gene first cloned from laryngeal squamous cell carcinoma. The downregulation of MYCT1 …
gene first cloned from laryngeal squamous cell carcinoma. The downregulation of MYCT1 …
[HTML][HTML] Promoter hypermethylation-induced transcriptional down-regulation of the gene MYCT1in laryngeal squamous cell carcinoma
M Yang, W Li, YY Liu, S Fu, GB Qiu, KL Sun, WN Fu - BMC cancer, 2012 - Springer
Background MYCT1, previously named MTLC, is a novel candidate tumor suppressor gene.
MYCT1 was cloned from laryngeal squamous cell cancer (LSCC) and has been found to be …
MYCT1 was cloned from laryngeal squamous cell cancer (LSCC) and has been found to be …
[HTML][HTML] MUC15 is an independent prognostic factor that promotes metastases of MYCN non-amplified neuroblastoma
H Guo, WX Zhang, Q Zhang, M Li, HY Wang… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Neuroblastoma (NB) is a cancer that arises from neural-crest-derived
sympathoadrenal lineage. Less is known about the pathogenesis and molecular …
sympathoadrenal lineage. Less is known about the pathogenesis and molecular …
Transmembrane domain is crucial to the subcellular localization and function of Myc target 1
Deregulation of c‐MYC occurs in a variety of human cancers. Overexpression of c‐MYC
promotes cell growth, proliferation, apoptosis, transformation and genomic instability. MYC …
promotes cell growth, proliferation, apoptosis, transformation and genomic instability. MYC …
[HTML][HTML] Gene signatures in wound tissue as evidenced by molecular profiling in the chick embryo model
Background Modern functional genomic approaches may help to better understand the
molecular events involved in tissue morphogenesis and to identify molecular signatures and …
molecular events involved in tissue morphogenesis and to identify molecular signatures and …