Local anesthetic systemic toxicity (LAST) is a life-threatening adverse event that may occur
after the administration of local anesthetic drugs through a variety of routes. Increasing use …

Abstract The American Society of Regional Anesthesia and Pain Medicine's Third Practice
Advisory on local anesthetic systemic toxicity is an interim update from its 2010 advisory …

Animal experimentation is widely used around the world for the identification of the root
causes of various diseases in humans and animals and for exploring treatment options …

Neurologic injury associated with regional anesthetic or pain medicine procedures is
extremely rare. The Second American Society of Regional Anesthesia and Pain Medicine …

Guidelines Update for Cardiopulmonary Resuscitation (CPR) and Emergency
Cardiovascular Care (ECC) addresses cardiac arrest in situations that require special …

The most widely used medications in dentistry are local anesthetics (LA), especially
lidocaine, and the number of recorded adverse allergic responses, particularly of hazardous …

This section of the 2010 AHA Guidelines for CPR and ECC addresses cardiac arrest in
situations that require special treatments or procedures beyond those provided during basic …

Background and Objectives Local anesthetic systemic toxicity (LAST) is a potentially life-
threatening complication of local anesthetic administration. In this article, the results of the …

This review summarizes presenting features, management, and outcomes of local
anesthetic systemic toxicity (LAST) from published cases and those submitted to online …

Background: The objective of this narrative review of local anesthetic systemic toxicity is to
provide an update on its prevention, diagnosis, and management. Methods: The authors …