[HTML][HTML] Crosstalk between mesenchymal stromal cells and tumor-associated macrophages in gastric cancer

P Zheng, W Li - Frontiers in Oncology, 2020 - frontiersin.org
Tumor microenvironment (TME) consisting of distinct cell types including stromal cells and
immune cells has recently emerged as a pivotal player in tumor development and …

M1-like TAMs are required for the efficacy of PD-L1/PD-1 blockades in gastric cancer

R Zhao, Q Wan, Y Wang, Y Wu, S Xiao, Q Li… - …, 2021 - Taylor & Francis
The efficacy of PD-1/PD-L1 blockades is heterogeneous in different molecular subtypes of
gastric cancer (GC). In this study, we analyzed relevant clinical trials to identify the molecular …

[HTML][HTML] Network pharmacology study and experimental validation of Yiqi Huayu decoction inducing ferroptosis in gastric cancer

S Song, F Wen, S Gu, P Gu, W Huang, S Ruan… - Frontiers in …, 2022 - frontiersin.org
Objective This study aimed to identify the mechanism of Yiqi Huayu Decoction (YQHY)
induced ferroptosis in gastric cancer (GC) by using network pharmacology and experimental …

Identification of Core Prognosis‐Related Candidate Genes in Chinese Gastric Cancer Population Based on Integrated Bioinformatics

M Li, X Wang, J Liu, X Mao, D Li, Z Wang… - BioMed research …, 2020 - Wiley Online Library
Background. Gastric cancer (GC) is one of the leading causes of cancer‐related mortality
worldwide. There are great geographical differences in the incidence of GC, and somatic …

Immunological effects and activity of multiple doses of zolbetuximab in combination with zoledronic acid and interleukin-2 in a phase 1 study in patients with advanced …

F Lordick, P Thuss-Patience, M Bitzer, D Maurus… - Journal of Cancer …, 2023 - Springer
Purpose Zolbetuximab (IMAB362) is engineered to induce antibody-dependent cell-
mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity. We evaluated ADCC …

Efficacy and Safety of Traditional Chinese Medicines as a Complementary Therapy Combined With Chemotherapy in the Treatment of Gastric Cancer: An Overview of …

W Xie, Y Zhang, J Tang, X Zhu… - Integrative Cancer …, 2024 - journals.sagepub.com
Background: In China, traditional Chinese medicines (TCMs), as a complementary therapy
combined with chemotherapy, is widely used in the treatment of gastric cancer (GC). In order …

Brasiliensic acid: in vitro cytotoxic and genotoxic, in vivo acute toxicity and in silico pharmacological prediction of a new promising molecule

LMS Lemos, OA Ọlọ́ba-Whẹ̀nù, IA Olasupo… - Journal of …, 2023 - Taylor & Francis
Brasiliensic acid (Bras) is a chromanone isolated from Calophyllum brasiliense Cambèss.
bark extracts with confirmed potential activity on gastric ulcer and Helicobacter pylori …

Dehydroabietic acid is a novel survivin inhibitor for gastric cancer

WJ Kim, W Kim, JM Bae, J Gim, SJ Kim - Plants, 2021 - mdpi.com
Gastric cancer is a malignant tumor with a high incidence and mortality rate worldwide.
Nevertheless, anticancer drugs that can be used for gastric cancer treatment are limited …

Perioperative safety and effectiveness of neoadjuvant therapy with fluorouracil, leucovorin, oxaliplatin, and docetaxel plus apatinib in locally advanced gastric cancer

Y Zhang, B Zhang, J Yang, J Zhang… - Cancer management …, 2021 - Taylor & Francis
Purpose The trend in neoadjuvant therapy for locally advanced gastric cancer (LAGC) is to
use more drugs or therapies in combination. This study aimed to assess the safety and …

Preclinical evaluation of oncolytic potential human rotavirus Wt 1-5 in gastric adenocarcinoma

H Sossa-Rojas, PG Franco-Maz, C Zapata-Acevedo… - Plos one, 2023 - journals.plos.org
Despite advances in biomedical research, gastric cancer remains the leading cause of
morbidity and mortality worldwide due to the limited efficacy of conventional therapies. In …