Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease

Q Yue, MPM Hoi - Neural Regeneration Research, 2023 - journals.lww.com
Blood-brain barrier disruption occurs in the early stages of Alzheimer's disease. Recent
studies indicate a link between blood-brain barrier dysfunction and cognitive decline and …

[HTML][HTML] Hydrogen sulfide and its donors for the treatment of cerebral ischaemia-reperfusion injury: A comprehensive review

Y Huang, M Omorou, M Gao, C Mu, W Xu… - Biomedicine & …, 2023 - Elsevier
As an endogenous gas signalling molecule, hydrogen sulfide (H 2 S) is frequently present in
a variety of mammals and plays a significant role in the cardiovascular and nervous systems …

Post-stroke impairment of the blood–brain barrier and perifocal vasogenic edema is alleviated by endovascular mesenchymal stem cell administration: modulation of …

A Datta, D Sarmah, H Kaur, A Chaudhary… - Molecular …, 2022 - Springer
Post-stroke edema and upregulation of aquaporin 4 (AQP4) water transport channels play a
significant role in the progression of stroke pathology and deteriorating stroke outcomes …

Oligodendrocytes play a critical role in white matter damage of vascular dementia

H Zhang, Y Yang, J Zhang, L Huang, Y Niu, H Chen… - Neuroscience, 2023 - Elsevier
With the deepening of population aging, the treatment of cognitive impairment and dementia
is facing increasing challenges. Vascular dementia (VaD) is a cognitive dysfunction caused …

Carbon dioxide and MAPK signalling: towards therapy for inflammation

H Gałgańska, W Jarmuszkiewicz… - Cell Communication and …, 2023 - Springer
Inflammation, although necessary to fight infections, becomes a threat when it exceeds the
capability of the immune system to control it. In addition, inflammation is a cause and/or …

[HTML][HTML] The apoptotic body membrane derived from T lymphocytes is used as an enzyme carrier to treat ischemic stroke

ZR Zou, S Wen, YQ Li, Q Wu, JY An, L Tong, H Guo… - Materials & Design, 2023 - Elsevier
Stroke is a high-morbidity central nervous system disease. Its complex pathological process
often leads to impaired consciousness, disability and even death. Currently, stroke is treated …

Neuroprotective effect of semaglutide in endotoxemia mouse model

AA Shnaien, AR Mohammad, ES Hassan - … Journal of War and Public Health, 2023 - ijwph.ir
Aims: This study was done to investigate the potential neuroprotective effect of semaglutide
during endotoxemia in mice. Material and method: 24 adult male Swiss-albino mice aged 8 …

Crosstalk among mitophagy, pyroptosis, ferroptosis, and necroptosis in central nervous system injuries

L Zhang, Z Hu, Z Li, Y Lin - Neural Regeneration Research, 2024 - journals.lww.com
Central nervous system injuries have a high rate of resulting in disability and mortality;
however, at present, effective treatments are lacking. Programmed cell death, which is a …

Mechanism of Astragalus mongholicus Bunge ameliorating cerebral ischemia-reperfusion injury: Based on network pharmacology analysis and experimental …

R Li, Q Lou, T Ji, Y Li, H Yang, Z Ma, Y Zhu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Astragalus mongholicus Bunge (AMB) is a herb
with wide application in traditional Chinese medicine, exerting a wealth of pharmacological …

Morphine Induced Neuroprotection in Ischemic Stroke by Activating Autophagy Via mTOR-Independent Activation of the JNK1/2 Pathway

W Chi, Y Huang, P Li, X Wang, J Li, F Meng - Neurochemical Research, 2024 - Springer
Morphine (Mor) has exhibited efficacy in safeguarding neurons against ischemic injuries by
simulating ischemic/hypoxic preconditioning (I/HPC). Concurrently, autophagy plays a …