The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness

J Firth, N Siddiqi, AI Koyanagi, D Siskind… - The Lancet …, 2019 - thelancet.com
Background The poor physical health of people with mental illness is a multifaceted,
transdiagnostic, and global problem. People with mental illness have an increased risk of …

The association between first-episode psychosis and abnormal glycaemic control: systematic review and meta-analysis

BI Perry, G McIntosh, S Weich, S Singh… - The Lancet Psychiatry, 2016 - thelancet.com
Background Schizophrenia might share intrinsic inflammatory disease pathways with type 2
diabetes. We aimed to assess whether first-episode psychosis, which could be described as …

Metformin in prevention and treatment of antipsychotic induced weight gain: a systematic review and meta-analysis

VA de Silva, C Suraweera, SS Ratnatunga… - BMC psychiatry, 2016 - Springer
Background Most antipsychotics are associated with weight gain and other metabolic
complications. Several randomized trials have shown metformin to be effective, but this still …

Cholesterol and triglyceride levels in first-episode psychosis: systematic review and meta-analysis

T Pillinger, K Beck, B Stubbs… - The British Journal of …, 2017 - cambridge.org
Background The extent of metabolic and lipid changes in first-episode psychosis (FEP) is
unclear. Aims To investigate whether individuals with FEP and no or minimal antipsychotic …

Metabolic issues in patients affected by schizophrenia: clinical characteristics and medical management

A Ventriglio, A Gentile, E Stella, A Bellomo - Frontiers in neuroscience, 2015 - frontiersin.org
Patients affected by psychotic disorders are more likely to develop high rates of co-
morbidities, such as obesity, type 2 diabetes, dyslipidemias, hypertension, metabolic …

A systematic review of genetic variants associated with metabolic syndrome in patients with schizophrenia

S Malan-Mueller, S Kilian, LL van den Heuvel… - Schizophrenia …, 2016 - Elsevier
Metabolic syndrome (MetS) is a cluster of factors that increases the risk of cardiovascular
disease (CVD), one of the leading causes of mortality in patients with schizophrenia …

Disentangling genetic risks for metabolic syndrome

ES van Walree, IE Jansen, NY Bell, JE Savage… - Diabetes, 2022 - Am Diabetes Assoc
A quarter of the world's population is estimated to meet the criteria for metabolic syndrome
(MetS), a cluster of cardiometabolic risk factors that promote development of coronary artery …

The role of pharmacy in the management of cardiometabolic risk, metabolic syndrome and related diseases in severe mental illness: a mixed-methods systematic …

D Sud, E Laughton, R McAskill, E Bradley… - Systematic reviews, 2021 - Springer
Background Individuals with severe mental illness, eg schizophrenia have up to a 20%
shortened life expectancy compared to the general population. Cardiovascular disease, due …

[HTML][HTML] Accelerated aging in schizophrenia patients: the potential role of oxidative stress

OO Okusaga - Aging and disease, 2014 - ncbi.nlm.nih.gov
Several lines of evidence suggest that schizophrenia, a severe mental illness characterized
by delusions, hallucinations and thought disorder is associated with accelerated aging. The …

Systematic review of racial disparities in clozapine prescribing

JC Williams, J Harowitz, J Glover, C Tek… - Schizophrenia Research, 2020 - Elsevier
Objective To conduct a systematic review of published evidence on clozapine prescribing
disparities across racial and ethnic categories, estimate the size of these disparities, and …