Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting PCSK9 in Nonhuman Primate and Mouse Models

RG Lee, AM Mazzola, MC Braun, C Platt, SB Vafai… - Circulation, 2023 - Am Heart Assoc
Background: VERVE-101 is an investigational in vivo CRISPR base-editing medicine
designed to alter a single DNA base in the PCSK9 gene, permanently turn off hepatic …

Use of co‐design methodology in the development of cardiovascular disease secondary prevention interventions: a scoping review

J Talevski, ST Kulnik, RL Jessup, R Falls… - Health …, 2023 - Wiley Online Library
Introduction There is growing evidence to support the use of co‐design in developing
interventions across many disciplines. This scoping review aims to examine how co‐design …

How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases: a clinical consensus statement from …

RFE Pedretti, D Hansen, M Ambrosetti… - European journal of …, 2023 - academic.oup.com
A key factor to successful secondary prevention of cardiovascular disease (CVD) is optimal
patient adherence to treatment. However, unsatisfactory rates of adherence to treatment for …

[HTML][HTML] Posthospitalization follow-up of patients with heart failure using eHealth solutions: restricted systematic review

IM Morken, M Storm, JA Søreide, KH Urstad… - Journal of Medical …, 2022 - jmir.org
Background Heart failure (HF) is a clinical syndrome with high incidence rates, a substantial
symptom and treatment burden, and a significant risk of readmission within 30 days after …

Effectiveness of a non-physician community health-care provider-led intensive blood pressure intervention versus usual care on cardiovascular disease (CRHCP): an …

J He, N Ouyang, X Guo, G Sun, Z Li, J Mu, DW Wang… - The Lancet, 2023 - thelancet.com
Background Effectiveness of a non-physician community health-care provider-led intensive
blood pressure intervention on cardiovascular disease has not been established. We aimed …

[HTML][HTML] Cardiometabolic patient-related factors influencing the adherence to lifestyle changes and overall treatment: A review of the recent literature

V Kalantzi, IP Kalafati, V Belitsi, T Tsiampalis… - Life, 2023 - mdpi.com
It is well acknowledged that most of the modifiable risk factors for Cardiovascular Diseases
(CVDs) can be averted through lifestyle modifications beyond medication adherence. This …

Regular medication as a risk factor for intracranial aneurysms: A comparative case–control study

R Jabbarli, M Darkwah Oppong, M Chihi… - European stroke …, 2023 - journals.sagepub.com
Background: Previous medical history strongly contributes to the genesis of intracranial
aneurysms (IA). A possible impact of regular medication on the occurrence of abdominal …

Pharmacist interventions for medication adherence: Community guide economic reviews for cardiovascular disease

V Jacob, JA Reynolds, SK Chattopadhyay… - American journal of …, 2022 - Elsevier
Introduction Adherence to medications for cardiovascular disease and its risk factors is less
than optimal, although greater adherence to medication has been shown to reduce the risk …

[HTML][HTML] Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study

T Adachi, Y Tsunekawa, D Tanimura - Plos one, 2022 - journals.plos.org
The correlation between personality traits and health outcomes of primary prevention has
been examined. However, there is a lack of evidence on the association between the …

Mindfulness-based interventions for patients with cardiovascular disease: a focused review for practicing clinicians

SY Lee, EC Gathright, WC Wu… - Current cardiology …, 2023 - Springer
Abstract Purpose of Review With growing scientific and public interest in the health benefits
of mindfulness, clinicians increasingly face questions and solicitations for advice from …