Biotechnological domestication of pseudomonads using synthetic biology
Much of contemporary synthetic biology research relies on the use of bacterial chassis for
plugging-in and plugging-out genetic circuits and new-to-nature functionalities. However …
plugging-in and plugging-out genetic circuits and new-to-nature functionalities. However …
From dirt to industrial applications: Pseudomonas putida as a synthetic biology chassis for hosting harsh biochemical reactions
Highlights•SynBio needs chassis with superior genetic, biochemical, and physiological
traits.•Environmental bacteria are endowed with many advantageous metabolic properties.• …
traits.•Environmental bacteria are endowed with many advantageous metabolic properties.• …
The drive to life on wet and icy worlds
MJ Russell, LM Barge, R Bhartia, D Bocanegra… - Astrobiology, 2014 - liebertpub.com
This paper presents a reformulation of the submarine alkaline hydrothermal theory for the
emergence of life in response to recent experimental findings. The theory views life, like …
emergence of life in response to recent experimental findings. The theory views life, like …
A revised central dogma for the 21st century: All biology is cognitive information processing
Abstract Crick's Central Dogma has been a foundational aspect of 20th century biology,
describing an implicit relationship governing the flow of information in biological systems in …
describing an implicit relationship governing the flow of information in biological systems in …
[HTML][HTML] Pathways to cellular supremacy in biocomputing
Synthetic biology uses living cells as the substrate for performing human-defined
computations. Many current implementations of cellular computing are based on the …
computations. Many current implementations of cellular computing are based on the …
Understanding carbon catabolite repression in Escherichia coli using quantitative models
Carbon catabolite repression (CCR) controls the order in which different carbon sources are
metabolized. Although this system is one of the paradigms of the regulation of gene …
metabolized. Although this system is one of the paradigms of the regulation of gene …
Metabolic variability in bioprocessing: implications of microbial phenotypic heterogeneity
Phenotypic heterogeneity is a major issue in the context of industrial bioprocessing.
Stochasticity of gene expression is usually considered to be the main source of …
Stochasticity of gene expression is usually considered to be the main source of …
Frankenstein or a submarine alkaline vent: who is responsible for abiogenesis? Part 2: as life is now, so it must have been in the beginning
E Branscomb, MJ Russell - BioEssays, 2018 - Wiley Online Library
We argued in Part 1 of this series that because all living systems are extremely far‐from‐
equilibrium dynamic confections of matter, they must necessarily be driven to that state by …
equilibrium dynamic confections of matter, they must necessarily be driven to that state by …
[HTML][HTML] Antimicrobials before antibiotics: war, peace, and disinfectants
H Landecker - Palgrave Communications, 2019 - nature.com
This analysis of antimicrobials before antibiotics uses both biological and historical
approaches to examine the origins of contemporary antibiotic resistance in the decades …
approaches to examine the origins of contemporary antibiotic resistance in the decades …
[HTML][HTML] Contemporary tools for regulating gene expression in bacteria
Insights from novel mechanistic paradigms in gene expression control have led to the
development of new gene expression systems for bioproduction, control, and sensing …
development of new gene expression systems for bioproduction, control, and sensing …