[HTML][HTML] Epigallocatechin-3-gallate: A phytochemical as a promising drug candidate for the treatment of Parkinson's disease

Y Wang, S Wu, Q Li, W Lang, W Li, X Jiang… - Frontiers in …, 2022 - frontiersin.org
Epigallocatechin 3-gallate (EGCG), an abundant polyphenolic component derived from
green tea extract, possesses versatile bioactivities that can combat many diseases. During …

[HTML][HTML] Neuroprotection and disease modification by astrocytes and microglia in Parkinson disease

S Takahashi, K Mashima - Antioxidants, 2022 - mdpi.com
Oxidative stress and neuroinflammation are common bases for disease onset and
progression in many neurodegenerative diseases. In Parkinson disease, which is …

[HTML][HTML] Peripheral nerve stimulation: A neuromodulation-based approach

AM Luckey, K Adcock, S Vanneste - Neuroscience & Biobehavioral …, 2023 - Elsevier
Recent technological improvements have positioned us at the threshold of innovative
discoveries that will assist in new perspectives and avenues of research. Increased attention …

[HTML][HTML] Role of dopamine in the pathophysiology of Parkinson's disease

ZD Zhou, LX Yi, DQ Wang, TM Lim, EK Tan - Translational …, 2023 - Springer
A pathological feature of Parkinson's disease (PD) is the progressive loss of dopaminergic
neurons and decreased dopamine (DA) content in the substantia nigra pars compacta in PD …

[HTML][HTML] Overview of movement disorders secondary to drugs

JP Rissardo, N Vora, B Mathew, V Kashyap… - Clinics and …, 2023 - mdpi.com
Drug-induced movement disorders affect a significant percentage of individuals, and they
are commonly overlooked and underdiagnosed in clinical practice. Many comorbidities can …

[HTML][HTML] Internal ribosome entry site (IRES)-mediated translation and its potential for novel mRNA-based therapy development

R Marques, R Lacerda, L Romão - Biomedicines, 2022 - mdpi.com
Many conditions can benefit from RNA-based therapies, namely, those targeting internal
ribosome entry sites (IRESs) and their regulatory proteins, the IRES trans-acting factors …

[HTML][HTML] From the tyrosine hydroxylase hypothesis of Parkinson's disease to modern strategies: a short historical overview

WD Rausch, F Wang, K Radad - Journal of Neural Transmission, 2022 - Springer
A time span of 60 years covers the detection of catecholamines in the brain, their function in
movement and correlation to Parkinson's disease (PD). The clinical findings that orally given …

Brain‐derived extracellular vesicles: Potential diagnostic biomarkers for central nervous system diseases

X Xu, Z Iqbal, L Xu, C Wen, L Duan… - Psychiatry and …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are membrane‐enclosed nanovesicles secreted by cells into the
extracellular space and contain functional biomolecules, eg signaling receptors, bioactive …

[HTML][HTML] Recent advances in aptamer-based sensors for sensitive detection of neurotransmitters

JH Park, YS Eom, TH Kim - Biosensors, 2023 - mdpi.com
In recent years, there has been an increased demand for highly sensitive and selective
biosensors for neurotransmitters, owing to advancements in science and technology. Real …

[HTML][HTML] Neuroimaging Techniques in Differentiating Parkinson's Disease from Drug-Induced Parkinsonism: A Comprehensive Review

J Pitton Rissardo, ALF Caprara - Clinics and Practice, 2023 - mdpi.com
Neuroimaging can provide significant benefits in evaluating patients with movement
disorders associated with drugs. This literature review describes neuroimaging techniques …