[HTML][HTML] Epigallocatechin-3-gallate: A phytochemical as a promising drug candidate for the treatment of Parkinson's disease
Y Wang, S Wu, Q Li, W Lang, W Li, X Jiang… - Frontiers in …, 2022 - frontiersin.org
Epigallocatechin 3-gallate (EGCG), an abundant polyphenolic component derived from
green tea extract, possesses versatile bioactivities that can combat many diseases. During …
green tea extract, possesses versatile bioactivities that can combat many diseases. During …
[HTML][HTML] Neuroprotection and disease modification by astrocytes and microglia in Parkinson disease
S Takahashi, K Mashima - Antioxidants, 2022 - mdpi.com
Oxidative stress and neuroinflammation are common bases for disease onset and
progression in many neurodegenerative diseases. In Parkinson disease, which is …
progression in many neurodegenerative diseases. In Parkinson disease, which is …
[HTML][HTML] Peripheral nerve stimulation: A neuromodulation-based approach
Recent technological improvements have positioned us at the threshold of innovative
discoveries that will assist in new perspectives and avenues of research. Increased attention …
discoveries that will assist in new perspectives and avenues of research. Increased attention …
[HTML][HTML] Role of dopamine in the pathophysiology of Parkinson's disease
A pathological feature of Parkinson's disease (PD) is the progressive loss of dopaminergic
neurons and decreased dopamine (DA) content in the substantia nigra pars compacta in PD …
neurons and decreased dopamine (DA) content in the substantia nigra pars compacta in PD …
[HTML][HTML] Overview of movement disorders secondary to drugs
JP Rissardo, N Vora, B Mathew, V Kashyap… - Clinics and …, 2023 - mdpi.com
Drug-induced movement disorders affect a significant percentage of individuals, and they
are commonly overlooked and underdiagnosed in clinical practice. Many comorbidities can …
are commonly overlooked and underdiagnosed in clinical practice. Many comorbidities can …
[HTML][HTML] Internal ribosome entry site (IRES)-mediated translation and its potential for novel mRNA-based therapy development
R Marques, R Lacerda, L Romão - Biomedicines, 2022 - mdpi.com
Many conditions can benefit from RNA-based therapies, namely, those targeting internal
ribosome entry sites (IRESs) and their regulatory proteins, the IRES trans-acting factors …
ribosome entry sites (IRESs) and their regulatory proteins, the IRES trans-acting factors …
[HTML][HTML] From the tyrosine hydroxylase hypothesis of Parkinson's disease to modern strategies: a short historical overview
WD Rausch, F Wang, K Radad - Journal of Neural Transmission, 2022 - Springer
A time span of 60 years covers the detection of catecholamines in the brain, their function in
movement and correlation to Parkinson's disease (PD). The clinical findings that orally given …
movement and correlation to Parkinson's disease (PD). The clinical findings that orally given …
Brain‐derived extracellular vesicles: Potential diagnostic biomarkers for central nervous system diseases
X Xu, Z Iqbal, L Xu, C Wen, L Duan… - Psychiatry and …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are membrane‐enclosed nanovesicles secreted by cells into the
extracellular space and contain functional biomolecules, eg signaling receptors, bioactive …
extracellular space and contain functional biomolecules, eg signaling receptors, bioactive …
[HTML][HTML] Recent advances in aptamer-based sensors for sensitive detection of neurotransmitters
In recent years, there has been an increased demand for highly sensitive and selective
biosensors for neurotransmitters, owing to advancements in science and technology. Real …
biosensors for neurotransmitters, owing to advancements in science and technology. Real …
[HTML][HTML] Neuroimaging Techniques in Differentiating Parkinson's Disease from Drug-Induced Parkinsonism: A Comprehensive Review
J Pitton Rissardo, ALF Caprara - Clinics and Practice, 2023 - mdpi.com
Neuroimaging can provide significant benefits in evaluating patients with movement
disorders associated with drugs. This literature review describes neuroimaging techniques …
disorders associated with drugs. This literature review describes neuroimaging techniques …