[HTML][HTML] Oral squamous cell carcinomas: state of the field and emerging directions
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …
[HTML][HTML] The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation
Various forms of fibrosis, comprising tissue thickening and scarring, are involved in 40% of
deaths across the world. Since the discovery of scarless functional healing in fetuses prior to …
deaths across the world. Since the discovery of scarless functional healing in fetuses prior to …
[HTML][HTML] Scarless wound healing programmed by core-shell microneedles
Y Zhang, S Wang, Y Yang, S Zhao, J You… - Nature …, 2023 - nature.com
Effective reprogramming of chronic wound healing remains challenging due to the limited
drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing …
drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing …
[HTML][HTML] Significance of interleukin (IL)-4 and IL-13 in inflammatory arthritis
M Iwaszko, S Biały, K Bogunia-Kubik - Cells, 2021 - mdpi.com
Interleukin (IL)-4 and IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-
5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important …
5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important …
[HTML][HTML] Differentiation and Regulation of TH Cells: A Balancing Act for Cancer Immunotherapy
A Basu, G Ramamoorthi, G Albert, C Gallen… - Frontiers in …, 2021 - frontiersin.org
Current success of immunotherapy in cancer has drawn attention to the subsets of TH cells
in the tumor which are critical for activation of anti-tumor response either directly by …
in the tumor which are critical for activation of anti-tumor response either directly by …
Cytokine storm and sepsis disease pathogenesis
BG Chousterman, FK Swirski, GF Weber - Seminars in immunopathology, 2017 - Springer
Infectious diseases are a leading cause of death worldwide. Sepsis is a severe clinical
syndrome related to the host response to infection. The severity of infections is due to an …
syndrome related to the host response to infection. The severity of infections is due to an …
[HTML][HTML] Type 2 immunity in tissue repair and fibrosis
Type 2 immunity is characterized by the production of IL-4, IL-5, IL-9 and IL-13, and this
immune response is commonly observed in tissues during allergic inflammation or infection …
immune response is commonly observed in tissues during allergic inflammation or infection …
Mast cells as sources of cytokines, chemokines, and growth factors
Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …
represent potential sources of a wide variety of biologically active secreted products …
Inflammation and metabolism in tissue repair and regeneration
Tissue repair after injury is a complex, metabolically demanding process. Depending on the
tissue's regenerative capacity and the quality of the inflammatory response, the outcome is …
tissue's regenerative capacity and the quality of the inflammatory response, the outcome is …
Commonality of the IL-4/IL-13 pathway in atopic diseases
NA Gandhi, G Pirozzi, NMH Graham - Expert review of clinical …, 2017 - Taylor & Francis
Introduction: Allergy results from an aberrant Type 2 inflammatory response, triggered by a
wide range of environmental antigens (allergens) that lead to various immune responses …
wide range of environmental antigens (allergens) that lead to various immune responses …