Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer

O Slaby, J Bienertova‐Vasku… - Journal of cellular …, 2012 - Wiley Online Library
Introduction• Classification of miRNA‐related SNPs‐SNPs in miRNA processing machinery‐
SNPs in pri‐, pre‐, mat‐miRNAs‐SNPs in miRNA‐binding sites• MiRNA‐related SNPs and …

A 3′-untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysis

T Paranjape, H Heneghan, R Lindner, FK Keane… - The lancet …, 2011 - thelancet.com
Background We previously identified a functional variant in a let-7 microRNA (miRNA)
complementary site in the 3′-untranslated region of the KRAS oncogene (rs61764370) …

[HTML][HTML] SNPs in miRNAs and target sequences: role in cancer and diabetes

Y Chhichholiya, AK Suryan, P Suman, A Munshi… - Frontiers in …, 2021 - frontiersin.org
miRNAs are fascinating molecular players for gene regulation as individual miRNA can
control multiple targets and a single target can be regulated by multiple miRNAs. Loss of …

[HTML][HTML] Mechanisms and role of microRNA deregulation in cancer onset and progression

EI Palmero, SGP de Campos, M Campos… - … and molecular biology, 2011 - SciELO Brasil
MicroRNAs are key regulators of various fundamental biological processes and, although
representing only a small portion of the genome, they regulate a much larger population of …

[HTML][HTML] Comprehensive review of genetic association studies and meta-analyses on miRNA polymorphisms and cancer risk

K Srivastava, A Srivastava - PloS one, 2012 - journals.plos.org
Background MicroRNAs (miRNAs) are small RNA molecules that regulate the expression of
corresponding messenger RNAs (mRNAs). Variations in the level of expression of distinct …

[HTML][HTML] miR-196a downregulation increases the expression of type I and III collagens in keloid fibroblasts

K Kashiyama, N Mitsutake, M Matsuse, T Ogi… - Journal of Investigative …, 2012 - Elsevier
Keloids are a fibroproliferative disease due to abnormal wound healing process after skin
injury. They are characterized by overproduction of extracellular matrix (ECM) such as …

Next generation sequencing reveals microRNA isoforms in liver cirrhosis and hepatocellular carcinoma

A Wojcicka, M Swierniak, O Kornasiewicz… - The international journal …, 2014 - Elsevier
Hepatocellular carcinoma (HCC) represents the major histological subtype of liver cancer.
Tumorigenic changes in hepatic cells potentially result from aberrant expression of …

[HTML][HTML] Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer

R Hezova, A Kovarikova… - World journal of …, 2012 - ncbi.nlm.nih.gov
AIM: To investigate whether selected single nucleotide polymorphisms (SNPs) in miR-
196a2, miR-27a and miR-146a genes are associated with sporadic colorectal cancer …

[HTML][HTML] The role of microRNAs in epithelial ovarian cancer metastasis

VHL Nguyen, C Yue, KY Du, M Salem… - International journal of …, 2020 - mdpi.com
Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and the major cause
of death is mainly attributed to metastasis. MicroRNAs (miRNAs) are a group of small non …

[HTML][HTML] Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies

XP Ma, T Zhang, B Peng, L Yu, DK Jiang - PloS one, 2013 - journals.plos.org
MicroRNAs (miRNAs) are small non-coding RNA molecules, which participate in diverse
biological processes and may regulate tumor suppressor genes or oncogenes. Single …