Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer
O Slaby, J Bienertova‐Vasku… - Journal of cellular …, 2012 - Wiley Online Library
Introduction• Classification of miRNA‐related SNPs‐SNPs in miRNA processing machinery‐
SNPs in pri‐, pre‐, mat‐miRNAs‐SNPs in miRNA‐binding sites• MiRNA‐related SNPs and …
SNPs in pri‐, pre‐, mat‐miRNAs‐SNPs in miRNA‐binding sites• MiRNA‐related SNPs and …
A 3′-untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysis
T Paranjape, H Heneghan, R Lindner, FK Keane… - The lancet …, 2011 - thelancet.com
Background We previously identified a functional variant in a let-7 microRNA (miRNA)
complementary site in the 3′-untranslated region of the KRAS oncogene (rs61764370) …
complementary site in the 3′-untranslated region of the KRAS oncogene (rs61764370) …
[HTML][HTML] SNPs in miRNAs and target sequences: role in cancer and diabetes
miRNAs are fascinating molecular players for gene regulation as individual miRNA can
control multiple targets and a single target can be regulated by multiple miRNAs. Loss of …
control multiple targets and a single target can be regulated by multiple miRNAs. Loss of …
[HTML][HTML] Mechanisms and role of microRNA deregulation in cancer onset and progression
EI Palmero, SGP de Campos, M Campos… - … and molecular biology, 2011 - SciELO Brasil
MicroRNAs are key regulators of various fundamental biological processes and, although
representing only a small portion of the genome, they regulate a much larger population of …
representing only a small portion of the genome, they regulate a much larger population of …
[HTML][HTML] Comprehensive review of genetic association studies and meta-analyses on miRNA polymorphisms and cancer risk
K Srivastava, A Srivastava - PloS one, 2012 - journals.plos.org
Background MicroRNAs (miRNAs) are small RNA molecules that regulate the expression of
corresponding messenger RNAs (mRNAs). Variations in the level of expression of distinct …
corresponding messenger RNAs (mRNAs). Variations in the level of expression of distinct …
[HTML][HTML] miR-196a downregulation increases the expression of type I and III collagens in keloid fibroblasts
K Kashiyama, N Mitsutake, M Matsuse, T Ogi… - Journal of Investigative …, 2012 - Elsevier
Keloids are a fibroproliferative disease due to abnormal wound healing process after skin
injury. They are characterized by overproduction of extracellular matrix (ECM) such as …
injury. They are characterized by overproduction of extracellular matrix (ECM) such as …
Next generation sequencing reveals microRNA isoforms in liver cirrhosis and hepatocellular carcinoma
A Wojcicka, M Swierniak, O Kornasiewicz… - The international journal …, 2014 - Elsevier
Hepatocellular carcinoma (HCC) represents the major histological subtype of liver cancer.
Tumorigenic changes in hepatic cells potentially result from aberrant expression of …
Tumorigenic changes in hepatic cells potentially result from aberrant expression of …
[HTML][HTML] Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer
R Hezova, A Kovarikova… - World journal of …, 2012 - ncbi.nlm.nih.gov
AIM: To investigate whether selected single nucleotide polymorphisms (SNPs) in miR-
196a2, miR-27a and miR-146a genes are associated with sporadic colorectal cancer …
196a2, miR-27a and miR-146a genes are associated with sporadic colorectal cancer …
[HTML][HTML] The role of microRNAs in epithelial ovarian cancer metastasis
Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and the major cause
of death is mainly attributed to metastasis. MicroRNAs (miRNAs) are a group of small non …
of death is mainly attributed to metastasis. MicroRNAs (miRNAs) are a group of small non …
[HTML][HTML] Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies
XP Ma, T Zhang, B Peng, L Yu, DK Jiang - PloS one, 2013 - journals.plos.org
MicroRNAs (miRNAs) are small non-coding RNA molecules, which participate in diverse
biological processes and may regulate tumor suppressor genes or oncogenes. Single …
biological processes and may regulate tumor suppressor genes or oncogenes. Single …