Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies

XP Ma, T Zhang, B Peng, L Yu, DK Jiang - PloS one, 2013 - journals.plos.org
MicroRNAs (miRNAs) are small non-coding RNA molecules, which participate in diverse
biological processes and may regulate tumor suppressor genes or oncogenes. Single …

Mature MicroRNA Sequence Polymorphism in MIR196A2 Is Associated with Risk and Prognosis of Head and Neck Cancer

BC Christensen, M Avissar-Whiting, LG Ouellet… - Clinical Cancer …, 2010 - AACR
Purpose: The central role of microRNAs as regulators of translation has been well
established, whereas the relationships between genetic variation in microRNAs and disease …

Potential impact of microRNA gene polymorphisms in the pathogenesis of diabetes and atherosclerotic cardiovascular disease

I Elfaki, R Mir, MM Mir, FM AbuDuhier… - Journal of personalized …, 2019 - mdpi.com
MicroRNAs (miRNAs) are endogenous, small (18–23 nucleotides), non-coding RNA
molecules. They regulate the posttranscriptional expression of their target genes. MiRNAs …

[HTML][HTML] Genomic variations in non-coding RNAs: structure, function and regulation

D Bhartiya, V Scaria - Genomics, 2016 - Elsevier
The last decade has seen tremendous improvements in the understanding of human
variations and their association with human traits and diseases. The availability of high …

SNPing cancer in the bud: microRNA and microRNA-target site polymorphisms as diagnostic and prognostic biomarkers in cancer

DW Salzman, JB Weidhaas - Pharmacology & therapeutics, 2013 - Elsevier
MicroRNAs are master regulators of gene expression and control many biological pathways
such as cell growth, differentiation and apoptosis. Deregulation of microRNA expression and …

[HTML][HTML] miR-125a-5p is a prognostic biomarker that targets HDAC4 to suppress breast tumorigenesis

TH Hsieh, CY Hsu, CF Tsai, CY Long, CY Chai… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Identifying stably expressed tumor markers that can be used easily to detect cancer is
currently an important area of cancer research. By using miRNA microarray, we identified 20 …

Epigenetic regulation of miR‐196b expression in gastric cancer

KW Tsai, LY Hu, CW Wu, SC Li, CH Lai… - Genes …, 2010 - Wiley Online Library
MicroRNAs (miRNAs) are short noncoding RNAs that play important roles in cellular
processes and disease pathogenesis via the control of specific targeted gene expression …

miR-196a Overexpression and miR-196a2 Gene Polymorphism Are Prognostic Predictors of Oral Carcinomas

CJ Liu, MM Tsai, HF Tu, MT Lui, HW Cheng… - Annals of surgical …, 2013 - Springer
Background Oral squamous cell carcinoma (OSCC) is prevalent worldwide, and survival in
OSCC has not improved significantly in the last few decades. MicroRNAs have an important …

MicroRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer

YR Park, ST Lee, SL Kim, YC Liu… - International …, 2016 - spandidos-publications.com
Abstract Transmembrane-4-L6 family 1 (TM4SF1) is upregulated in colorectal carcinoma
(CRC). However, the mechanism leading to inhibition of the TM4SF1 is not known. In the …

Potential impact of GCK, MIR-196A-2 and MIR-423 gene abnormalities on the development and progression of type 2 diabetes mellitus in Asir and Tabuk regions of …

MM Mir, R Mir, MAA Alghamdi… - Molecular …, 2022 - spandidos-publications.com
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by persistent
hyperglycemia and is associated with serious complications. The risk factors for T2DM …