Pathogenicity and virulence of influenza

Y Liang - Virulence, 2023 - Taylor & Francis
Influenza viruses, including four major types (A, B, C, and D), can cause mild-to-severe and
lethal diseases in humans and animals. Influenza viruses evolve rapidly through antigenic …

Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Host recovery from respiratory viral infection

X Wei, H Narasimhan, B Zhu… - Annual Review of …, 2023 - annualreviews.org
Emerging and re-emerging respiratory viral infections pose a tremendous threat to human
society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the …

Recapitulation of pathophysiological features of AD in SARS-CoV-2-infected subjects

E Griggs, K Trageser, S Naughton, EJ Yang, B Mathew… - Elife, 2023 - elifesciences.org
Infection with the etiological agent of COVID-19, SARS-CoV-2, appears capable of
impacting cognition in some patients with post-acute sequelae of SARS-CoV-2 (PASC). To …

Viral infections during pregnancy: the big challenge threatening maternal and fetal health

W Yu, X Hu, B Cao - Maternal-Fetal Medicine, 2022 - mednexus.org
Viral infections during pregnancy are associated with adverse pregnancy outcomes,
including maternal and fetal mortality, pregnancy loss, premature labor, and congenital …

Tetracycline-induced mitohormesis mediates disease tolerance against influenza

A Mottis, TY Li, G El Alam, A Rapin… - The Journal of …, 2022 - Am Soc Clin Investig
Mitohormesis defines the increase in fitness mediated by adaptive responses to mild
mitochondrial stress. Tetracyclines inhibit not only bacterial but also mitochondrial …

Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates

J Corry, G Kettenburg, AA Upadhyay, M Wallace… - PLoS …, 2022 - journals.plos.org
Severe influenza kills tens of thousands of individuals each year, yet the mechanisms
driving lethality in humans are poorly understood. Here we used a unique translational …

Cyanobacteria and algae-derived bioactive metabolites as antiviral agents: Evidence, mode of action, and scope for further expansion; a comprehensive review in …

B Pradhan, R Nayak, S Patra, PP Bhuyan, SR Dash… - Antioxidants, 2022 - mdpi.com
COVID-19—a severe acute respiratory syndrome disease caused by coronavirus 2 (SARS-
CoV-2)—has recently attracted global attention, due to its devastating impact, to the point of …

Inhaled drug delivery: Past, present, and future

L Yue, X Zhang, C Zhao, R Chen, X Chen, L Rao - Nano Today, 2023 - Elsevier
Inhaled drug delivery has been an emerging route for the treatment of lung diseases with
clear advantages over oral and intravenous routes. However, the delivery efficacy is affected …

Immune determinants of chronic sequelae after respiratory viral infection

H Narasimhan, Y Wu, NP Goplen, J Sun - Science Immunology, 2022 - science.org
The acute effects of various respiratory viral infections have been well studied, with
extensive characterization of the clinical presentation as well as viral pathogenesis and host …