Infertility is a complex disorder with multiple genetic and environmental causes. Although
some specific mutations have been identified, other factors responsible for sperm defects …

Sperm-specific phospholipase C zeta (PLCζ) is widely considered to be the physiological
stimulus responsible for generating calcium (Ca2+) oscillations that induce egg activation …

DNA repair processes are critical to maintaining genomic integrity. As a result, dysregulation
of repair genes is likely to be linked with health implications, such as an increased …

We used a gas chromatography-mass spectrometry (GC-MS) based metabolomics
approach to obtain the metabolic profiling of unexplained male infertility (UMI), and identified …

Introduction The relation between infertility and sexual dysfunction can be reciprocal.
Causes of sexual dysfunction that affect fertility include erectile dysfunction, Peyronie's …

New genetic causes and genetic risk factors have been identified in recent years and new
technologies for genomic and postgenomic analyses (arrays, next-generation sequencing …

When couples cannot achieve pregnancy, they often seek health care from medical and
nursing specialists. The care the couple receives begins with a thorough assessment to …

Purpose Oocyte activation is a fundamental event at mammalian fertilization. In mammals,
this process is initiated by a series of characteristic calcium (Ca 2+) oscillations, induced by …

Oocyte activation is a fundamental event at mammalian fertilisation, initiated by a series of
characteristic calcium (Ca 2+) oscillations in mammals. This characteristic pattern of Ca 2+ …

Mammalian sex chromosomes evolved from an ordinary pair of autosomes. The X
chromosome is highly conserved, whereas the Y chromosome varies among species in size …