Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The liver is the major organ that metabolizes alcohol; …

Hepatocellular carcinoma (HCC) is associated with chronic inflammation and fibrosis arising
from different etiologies, including hepatitis B and C and alcoholic and nonalcoholic fatty …

Alcohol-related liver disease is the most prevalent type of chronic liver disease worldwide,
accounting for 30% of hepatocellular carcinoma (HCC) cases and HCC-specific deaths …

Alcohol is inextricably linked with the digestive system. It is absorbed through the gut and
metabolised by hepatocytes within the liver. Excessive alcohol use results in alterations to …

A major mitochondrial enzyme for protecting cells from acetaldehyde toxicity is aldehyde
dehydrogenase 2 (ALDH2). The correlation between ALDH2 dysfunction and …

The occurrence of more than 200 diseases, including cancer, can be attributed to alcohol
drinking. The global cancer deaths attributed to alcohol-consumption rose from 243,000 in …

Liver cancer, of which hepatocellular carcinoma (HCC) is the dominant variety, represents
the fourth leading cause of cancer deaths worldwide. The geographic map of the incidence …

Several scientific and clinical studies have shown an association between chronic alcohol
consumption and the occurrence of cancer in humans. The mechanism for alcohol-induced …

Public health guidelines aim to limit the consumption of alcoholic beverages worldwide and
the subsequent health burden. In particular, alcohol consumption is an avoidable risk factor …