Allergic rhinitis: pathophysiology and treatment focusing on mast cells

Y Zoabi, F Levi-Schaffer, R Eliashar - Biomedicines, 2022 - mdpi.com
Allergic rhinitis (AR) is a common rhinopathy that affects up to 30% of the adult population. It
is defined as an inflammation of the nasal mucosa, develops in allergic individuals, and is …

Antihistamines in children and adolescents: A practical update

GF Parisi, S Leonardi, G Ciprandi, A Corsico… - Allergologia et …, 2020 - Elsevier
Histamine is a chemical mediator, released predominantly by tissue mast cells, circulating
basophils, and neurons, which are activated in response to various immunological and non …

Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling

N Iwasaki, S Terawaki, K Shimizu, D Oikawa… - Plos one, 2021 - journals.plos.org
Histamine, which is mainly produced by mast cells and basophils, participates in various
allergic symptoms, and some studies have reported that macrophages also produce …

Literature-based discovery predicts antihistamines are a promising repurposed adjuvant therapy for Parkinson's disease

G Tandra, A Yoone, R Mathew, M Wang… - International Journal of …, 2023 - mdpi.com
Parkinson's disease (PD) is a movement disorder caused by a dopamine deficit in the brain.
Current therapies primarily focus on dopamine modulators or replacements, such as …

Synthesis, structural elucidation, molecular modeling, and antimicrobial studies of some nanoparticles mixed ligands complexes of cetirizine in presence of 2, 2 …

AE Salem, SF Mohammed, SA Sadeek… - Applied …, 2022 - Wiley Online Library
A four mixed ligand metal complexes derived from the interaction of Cu (II), Zn (II), Zr (IV),
and Cd (II) with antihistamine cetirizine. 2HCl (Cetz) in the presence of 2, 2′‐bipyridine …

Focus on the cetirizine use in clinical practice: a reappraisal 30 years later

AG Corsico, S Leonardi, A Licari, G Marseglia… - Multidisciplinary …, 2019 - Springer
Antihistamines are currently one of the most commonly administered categories of drugs.
They are used to treat symptoms that are secondary to histamine release, which is typical of …

Antihistamines: ABC for the pediatricians

GF Parisi, A Licari, M Papale, S Manti… - Pediatric Allergy and …, 2020 - Wiley Online Library
Antihistamines are currently one of the most commonly administered drugs in children. They
are used to treat symptoms that depend on histamine release, namely allergic diseases …

Antihistamines in children: A dermatological perspective

S Kohli, R Tayal, T Goyal - Indian Journal of Paediatric …, 2022 - journals.lww.com
Antihistamines are widely used drugs in pediatric population. First-generation
antihistamines have been in use since last many years, though adequate data on their …

Current and emerging pharmacotherapy for chronic spontaneous urticaria: a focus on non-biological therapeutics

KL Hon, JTS Li, AKC Leung… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Chronic spontaneous urticaria (CSU) refers to urticaria (wheals) or
angioedema, which occur for a period of six weeks or longer without an apparent cause. The …

[HTML][HTML] Influences of bifid triple viable capsules plus cetirizine on gut microbiota and immune function in children with eczema

Z Su, Y Kang - Drug Design, Development and Therapy, 2022 - ncbi.nlm.nih.gov
Objective Infantile eczema (IE), a common pediatric allergic skin disease caused by multiple
inherent and external factors, is common in infants and young children, with skin lesions and …