Alteration in microRNA expression governs the nature and timing of cellular fate commitment
D Sengupta, S Kar - ACS Chemical Neuroscience, 2017 - ACS Publications
In the central nervous system, the expression level of transcriptional repressor Hes1 (hairy
and enhancer of split-1) tightly controls the alternative cell fate commitment during …
and enhancer of split-1) tightly controls the alternative cell fate commitment during …
Dynamics of a miRNA model with two delays
S Nikolov, JV Gonzalez, M Nenov… - Biotechnology & …, 2012 - Taylor & Francis
MicroRNAs are a large class of post-transcriptional regulators of gene expression and they
have important regulatory functions in basic cellular processes. In this paper, mathematical …
have important regulatory functions in basic cellular processes. In this paper, mathematical …
Analysis of miRNA regulation suggests an explanation for 'unexpected'increase in target protein levels
SA Gokhale, CJ Gadgil - Molecular BioSystems, 2012 - pubs.rsc.org
MicroRNA (miRNA) has been mostly associated with decrease in target protein expression
levels. Recently,'unexpected'observations of increase in target protein expression attributed …
levels. Recently,'unexpected'observations of increase in target protein expression attributed …
[HTML][HTML] Slowly produced microRNAs control protein levels
Proteins are the primary agents of function in biological systems, and their levels are critical
control elements, reflecting the interplay between transcription, translation, and protein …
control elements, reflecting the interplay between transcription, translation, and protein …
Periodic perturbation of genetic oscillations
VP Zhdanov - Chaos, Solitons & Fractals, 2012 - Elsevier
Kinetics of gene expression may be oscillatory due to the feedbacks between the mRNA,
non-coding RNA and protein synthesis. In complex genetic networks, the kinetic oscillations …
non-coding RNA and protein synthesis. In complex genetic networks, the kinetic oscillations …
Stability and Hopf bifurcation analysis in a delayed three-node circuit involving interlinked positive and negative feedback loops
G Wang, Z Yang, M Turcotte - Mathematical Biosciences, 2019 - Elsevier
A system involving interlinked positive and negative feedback loops is a flexible motif that
can tune itself in gene regulatory networks. It is well known that time delay is inevitable in …
can tune itself in gene regulatory networks. It is well known that time delay is inevitable in …
Stability and Hopf Bifurcation Analysis in a Delayed Myc/E2F/miR‐17‐92 Network Involving Interlinked Positive and Negative Feedback Loops
G Wang, Z Yang - Discrete Dynamics in Nature and Society, 2018 - Wiley Online Library
MiR‐17‐92 plays an important role in regulating the levels of the Myc/E2F protein. In this
paper, we consider a coupling network between Myc/E2F/miR‐17‐92 delayed negative …
paper, we consider a coupling network between Myc/E2F/miR‐17‐92 delayed negative …
Coherence resonance in a noise-driven gene network regulated by small RNA
Small RNA has recently drawn more and more attention. In this paper, we concentrate on
the influence of noises on gene network regulated by small RNA using chemical Langevin …
the influence of noises on gene network regulated by small RNA using chemical Langevin …
A simple method for incorporating dynamic effects of intronic miRNA mediated regulation
S Gokhale, M Hariharan, SK Brahmachari… - Molecular …, 2012 - pubs.rsc.org
The importance of microRNA (miRNA) in modulating gene expression at the post-
transcriptional level is well known. Such regulation has been shown to influence the …
transcriptional level is well known. Such regulation has been shown to influence the …
Hierarchical genetic networks and noncoding RNAs
VP Zhdanov - Chaos: An Interdisciplinary Journal of Nonlinear …, 2010 - pubs.aip.org
In eukaryotic cells, many genes are transcribed into noncoding RNAs. Such RNAs may
associate with mRNAs and inhibit their translation and facilitate degradation. To clarify what …
associate with mRNAs and inhibit their translation and facilitate degradation. To clarify what …