Executive summary Despite substantial progress in reducing the global impact of many non-
communicable diseases, including heart disease and cancer, morbidity and mortality due to …

Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
that seriously threatens human health and life. Due to its high reactivity, cytotoxicity and …

Importance Chronic obstructive pulmonary disease (COPD) is a respiratory condition that is
associated with significant health and economic burden worldwide. Previous studies …

Amongst the lysosomal cysteine cathepsin family of proteases, cathepsin S (CTSS) holds
particular interest due to distinctive properties including a normal restricted expression …

Background COPD and adult-onset asthma (AOA) are the most common noncommunicable
respiratory diseases. To improve early identification and prevention, an overview of risk …

Chronic exposure to indoor biomass smoke from the combustion of solid organic fuels is a
major cause of disease burden worldwide. Almost 3 billion people use solid fuels such as …

Chronic obstructive pulmonary disease (COPD) is a common chronic disease characterized
by chronic airway inflammation and remodeling, which seriously endangers human health …

Background Preterm birth affects lungs in several ways but few studies have follow-up until
adulthood. We investigated the association of the entire spectrum of gestational ages with …

Messenger RNA (mRNA) technology has already been successfully tested preclinically and
there are ongoing clinical trials for protein replacement purposes; however, more effort has …

Background Environmental exposures are major risk factors for chronic obstructive
pulmonary disease (COPD). Ethylene oxide (EO) is a ubiquitous organic compound and …