Reward, dopamine and the control of food intake: implications for obesity

ND Volkow, GJ Wang, RD Baler - Trends in cognitive sciences, 2011 - cell.com
The ability to resist the urge to eat requires the proper functioning of neuronal circuits
involved in top-down control to oppose the conditioned responses that predict reward from …

Obesity and appetite control

K Suzuki, CN Jayasena… - Journal of Diabetes …, 2012 - Wiley Online Library
Obesity is one of the major challenges to human health worldwide; however, there are
currently no effective pharmacological interventions for obesity. Recent studies have …

Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome

AL Dinel, C Andre, A Aubert, G Ferreira, S Laye… - PloS one, 2011 - journals.plos.org
Converging clinical data suggest that peripheral inflammation is likely involved in the
pathogenesis of the neuropsychiatric symptoms associated with metabolic syndrome (MetS) …

Feeding and reward are differentially induced by activating GABAergic lateral hypothalamic projections to VTA

MF Barbano, HL Wang, M Morales… - Journal of …, 2016 - Soc Neuroscience
Electrical stimulation of the lateral hypothalamus (LH) has two motivational effects: long
trains of stimulation induce drive-like effects such as eating, and short trains are rewarding. It …

Melatonin absence leads to long-term leptin resistance and overweight in rats

D Buonfiglio, R Parthimos, R Dantas… - Frontiers in …, 2018 - frontiersin.org
Melatonin (Mel), a molecule that conveys photoperiodic information to the organisms, is also
involved in the regulation of energy homeostasis. Mechanisms of action of Mel in the energy …

Impact of prebiotics on metabolic and behavioral alterations in a mouse model of metabolic syndrome

LF De Cossio, C Fourrier, J Sauvant, A Everard… - Brain, behavior, and …, 2017 - Elsevier
Mounting evidence shows that the gut microbiota, an important player within the gut-brain
communication axis, can affect metabolism, inflammation, brain function and behavior …

Neural bases of food perception: Coordinate‐based meta‐analyses of neuroimaging studies in multiple modalities

CI Huerta, PR Sarkar, TQ Duong, AR Laird, PT Fox - Obesity, 2014 - Wiley Online Library
Objective The purpose of this study was to compare the results of the three food‐cue
paradigms most commonly used for functional neuroimaging studies to determine: i) …

Mechanisms of body weight fluctuations in Parkinson's disease

A Kistner, E Lhommée, P Krack - Frontiers in neurology, 2014 - frontiersin.org
Typical body weight changes are known to occur in Parkinson's disease (PD). Weight loss
has been reported in early stages as well as in advanced disease and malnutrition may …

Neuroendocrine abnormalities in Parkinson's disease

E De Pablo-Fernández, DP Breen… - Journal of Neurology …, 2017 - jnnp.bmj.com
Neuroendocrine abnormalities are common in Parkinson's disease (PD) and include
disruption of melatonin secretion, disturbances of glucose, insulin resistance and bone …

The gut–brain axis in the neuropsychological disease model of obesity: a classical movie revised by the emerging director “Microbiome”

E Niccolai, F Boem, E Russo, A Amedei - Nutrients, 2019 - mdpi.com
The worldwide epidemic of obesity has become an important public health issue, with
serious psychological and social consequences. Obesity is a multifactorial disorder in which …