Interplay between lignans and gut microbiota: nutritional, functional and methodological aspects

S Baldi, M Tristán Asensi, M Pallecchi, F Sofi… - Molecules, 2023 - mdpi.com
Lignans are non-flavonoid polyphenols present in a wide range of foods frequently
consumed in the Western world, such as seeds, vegetables and fruits, and beverages such …

Delineating the role of nuclear receptors in colorectal cancer, a focused review

MK Manickasamy, S Jayaprakash, S Girisa, A Kumar… - Discover Oncology, 2024 - Springer
Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally,
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …

[HTML][HTML] Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness

B Refaat, A Aslam, S Idris, AH Almalki… - Frontiers in …, 2023 - frontiersin.org
Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …

Pathway2Targets: an open-source pathway-based approach to repurpose therapeutic drugs and prioritize human targets

MD Spendlove, TM Gibson, S McCain, BC Stone, T Gill… - PeerJ, 2023 - peerj.com
Background Recent efforts to repurpose existing drugs to different indications have been
accompanied by a number of computational methods, which incorporate protein-protein …

17β-estradiol in colorectal cancer: friend or foe?

Z Wu, C Xiao, J Wang, M Zhou, F You, X Li - Cell Communication and …, 2024 - Springer
Colorectal cancer (CRC) is a common gastrointestinal malignancy with higher incidence
and mortality rates in men compared to women, potentially due to the effects of estrogen …

High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer

G Topi, SR Satapathy, S Ghatak, K Hellman… - Cell Communication and …, 2024 - Springer
In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while
oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon …

Sex Differences in Colon Cancer: Genomic and Nongenomic Signalling of Oestrogen

BJ Harvey, HM Harvey - Genes, 2023 - mdpi.com
Colon cancer (CRC) is a prevalent malignancy that exhibits distinct differences in incidence,
prognosis, and treatment responses between males and females. These disparities have …

[HTML][HTML] BRAFV600E mutation enhances estrogen-induced metastatic potential of thyroid cancer by regulating the expression of estrogen receptors

M Kim, S Kim, SY Ha, Z Xu, Y Han… - Endocrinology and …, 2022 - synapse.koreamed.org
Background Cross-talk between mitogen-activated protein kinase and estrogen has been
reported; however, the role of BRAF V600E in the estrogen responsiveness of thyroid cancer …

[PDF][PDF] Background: Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR) receptors are pathologically altered in colorectal cancer (CRC), their …

VK Pidugu, S Ramadesikan, A Kulkarni, H Makala… - 2023 - academia.edu
Background: Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …