[HTML][HTML] Cannabinoids: therapeutic use in clinical practice

C Pagano, G Navarra, L Coppola, G Avilia… - International journal of …, 2022 - mdpi.com
Medical case reports suggest that cannabinoids extracted from Cannabis sativa have
therapeutic effects; however, the therapeutic employment is limited due to the psychotropic …

[HTML][HTML] Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Cannabidiol inhibits SARS‐Cov‐2 spike (S) protein‐induced cytotoxicity and inflammation through a PPARγ‐dependent TLR4/NLRP3/Caspase‐1 signaling …

C Corpetti, A Del Re, L Seguella, I Palenca… - Phytotherapy …, 2021 - Wiley Online Library
Given the abundancy of angiotensin converting enzyme 2 (ACE‐2) receptors density,
beyond the lung, the intestine is considered as an alternative site of infection and replication …

[HTML][HTML] Clinical relevance of drug interactions with cannabis: A systematic review

V Lopera, A Rodríguez, P Amariles - Journal of Clinical Medicine, 2022 - mdpi.com
Concomitant use of cannabis with other drugs may lead to cannabis–drug interactions,
mainly due to the pharmacokinetic mechanism involving the family of CYP450 isoenzymes …

[HTML][HTML] Anti-inflammatory and antiviral effects of cannabinoids in inhibiting and preventing SARS-CoV-2 infection

M Janecki, M Graczyk, AA Lewandowska… - International journal of …, 2022 - mdpi.com
The COVID-19 pandemic caused by the SARS-CoV-2 virus made it necessary to search for
new options for both causal treatment and mitigation of its symptoms. Scientists and …

[HTML][HTML] Cannabis sativa research trends, challenges, and new-age perspectives

T Hussain, G Jeena, T Pitakbut, N Vasilev, O Kayser - Iscience, 2021 - cell.com
Cannabis sativa L. has been one of the oldest medicinal plants cultivated for 10,000 years
for several agricultural and industrial applications. However, the plant became controversial …

[HTML][HTML] A review of natural products, their effects on SARS-CoV-2 and their utility as lead compounds in the discovery of drugs for the treatment of COVID-19

RL Chapman, SV Andurkar - Medicinal Chemistry Research, 2022 - Springer
During the COVID-19 pandemic lasting now for well more than a year, nearly 247 million
cases have been diagnosed and over 5 million deaths have been recorded worldwide as of …

[HTML][HTML] CRISPR-Cas gene editing technology and its application prospect in medicinal plants

M Guo, H Chen, S Dong, Z Zhang, H Luo - Chinese medicine, 2022 - Springer
The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas gene editing
technology has opened a new era of genome interrogation and genome engineering …

Cannabidiol for COVID-19 patients with mild to moderate symptoms (CANDIDATE Study): a randomized, double-blind, placebo-controlled clinical trial

JAS Crippa, JC Pacheco, AW Zuardi… - Cannabis and …, 2022 - liebertpub.com
Importance: Owing to its anti-inflammatory properties and antiviral “in vitro” effect against
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cannabidiol (CBD) has …

[HTML][HTML] Cannabis use, abuse and dependence during the COVID-19 pandemic: a scoping review

U Bonnet, M Specka, P Roser, N Scherbaum - Journal of Neural …, 2023 - Springer
The interaction between cannabis use or addiction and SARS-COV-2 infection rates and
COVID-19 outcomes is obscure. As of 08/01/2022 among 57 evaluated epidemiological …