HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

CCR5Δ32 in Brazil: Impacts of a european genetic variant on a highly admixed population

B Kulmann-Leal, JH Ellwanger, JAB Chies - Frontiers in Immunology, 2021 - frontiersin.org
The genetic background of Brazilians encompasses Amerindian, African, and European
components as a result of the colonization of an already Amerindian inhabited region by …

STLV-1 co-infection is correlated with an increased SFV proviral load in the peripheral blood of SFV/STLV-1 naturally infected non-human primates

S Alais, A Pasquier, B Jegado, C Journo… - PLoS Neglected …, 2018 - journals.plos.org
Simian T-Leukemia Virus type 1 and Simian Foamy Virus infect non-human primates. While
STLV-1, as HTLV-1, causes Adult T-cell Leukemia/lymphoma, SFV infection is …

Neurological aspects of HIV-1/HTLV-1 and HIV-1/HTLV-2 coinfection

AQC Araujo - Pathogens, 2020 - mdpi.com
Simultaneous infection by human immunodeficiency viruses (HIV) and human T-
lymphotropic viruses (HTLV) are not uncommon since they have similar means of …

[HTML][HTML] HTLV-1 Tax activates HIV-1 transcription in latency models

VEV Geddes, DP José, FE Leal, DF Nixon, A Tanuri… - Virology, 2017 - Elsevier
HIV-1 latency is a major obstacle to HIV-1 eradication. Coinfection with HTLV-1 has been
associated with faster progression to AIDS. HTLV-1 encodes the transactivator Tax which …

STLV-1 as a model for studying HTLV-1 infection

B Jégado, F Kashanchi, H Dutartre, R Mahieux - Retrovirology, 2019 - Springer
Few years after HTLV-1 identification and isolation in humans, STLV-1, its simian
counterpart, was discovered. It then became clear that STLV-1 is present almost in all simian …

HTLV-2 Enhances CD8+ T Cell-Mediated HIV-1 Inhibition and Reduces HIV-1 Integrated Proviral Load in People Living with HIV-1

M Abad-Fernández, FJ Hernández-Walias… - Viruses, 2022 - mdpi.com
People living with HIV-1 and HTLV-2 concomitantly show slower CD4+ T cell depletion and
AIDS progression, more frequency of the natural control of HIV-1, and lower mortality rates …

Biomarkers in a Cohort of HIV-Infected Patients Single-or Co-Infected with HTLV-1, HTLV-2, and/or HCV: A Cross-Sectional, Observational Study

A Caterino-de-Araujo, KR Campos, LMS Oliveira… - Viruses, 2022 - mdpi.com
HIV, HTLV-1/-2, and HCV share routes of transmission, and such virus co-infections could
account for worse outcomes of associated diseases. Measuring cytokines/chemokines, CD4 …

Human T-cell leukemia virus type 1-related diseases may constitute a threat to the elimination of human immunodeficiency virus, by 2030, in Gabon, Central Africa

EF Oloumbou, JD Engone-Ondo… - Viruses, 2022 - mdpi.com
The Joint United Nations Program on HIV/AIDS (UNAIDS) has adopted the Sustainable
Development Goals (SDGs) to end the HIV/AIDS epidemic by 2030. Several factors related …

[HTML][HTML] Effects of CCR5 59029G/A polymorphism on the risk to diabetic nephropathy

M Cao, Z Tian, L Zhang, R Liu, Q Guan, J Jiang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Diabetic nephropathy (DN) causes high mortality in patients with diabetes
mellitus and imposes heavy burden on individuals and society. In previous studies, various …