[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

M Ashrafizadeh, M Delfi, A Zarrabi, A Bigham… - Journal of controlled …, 2022 - Elsevier
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

(Nano) platforms in breast cancer therapy: drug/gene delivery, advanced nanocarriers and immunotherapy

M Ashrafizadeh, A Zarrabi, A Bigham… - Medicinal Research …, 2023 - Wiley Online Library
Breast cancer is the most malignant tumor in women, and there is no absolute cure for it.
Although treatment modalities including surgery, chemotherapy, and radiotherapy are …

[HTML][HTML] Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects

S Mirzaei, MH Gholami, F Hashemi, A Zabolian… - Drug Discovery …, 2022 - Elsevier
Abstract P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX)
resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2 …

Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

(Nano) platforms in bladder cancer therapy: Challenges and opportunities

M Ashrafizadeh, A Zarrabi… - Bioengineering & …, 2023 - Wiley Online Library
Urological cancers are among the most common malignancies around the world. In
particular, bladder cancer severely threatens human health due to its aggressive and …

Chitosan‐based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy

M Ashrafizadeh, K Hushmandi… - Bioengineering & …, 2023 - Wiley Online Library
Green chemistry has been a growing multidisciplinary field in recent years showing great
promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an …

[HTML][HTML] Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions

M Hashemi, S Etemad, S Rezaei, S Ziaolhagh… - Biomedicine & …, 2023 - Elsevier
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …

The role of microRNA-21 (miR-21) in pathogenesis, diagnosis, and prognosis of gastrointestinal cancers: A review

BF Far, K Vakili, M Fathi, S Yaghoobpoor, M Bhia… - Life sciences, 2023 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of several
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …

Integrated single-cell and bulk RNA sequencing analysis identifies a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses …

H Zheng, H Liu, Y Ge, X Wang - Cancer cell international, 2021 - Springer
Abstract Background Cancer-associated fibroblasts (CAFs) contribute notably to colorectal
cancer (CRC) tumorigenesis, stiffness, angiogenesis, immunosuppression and metastasis …

[HTML][HTML] Targeted therapies of curcumin focus on its therapeutic benefits in cancers and human health: Molecular signaling pathway-based approaches and future …

MR Islam, A Rauf, S Akash, SI Trisha, AH Nasim… - Biomedicine & …, 2024 - Elsevier
The curry powder spices turmeric (Curcuma longa L.), which contains curcumin
(diferuloylmethane), an orange-yellow chemical. Polyphenols are the most commonly used …