Targeted therapy for inflammatory diseases with mesenchymal stem cells and their derived exosomes: from basic to clinics

S Wang, B Lei, E Zhang, P Gong, J Gu… - International Journal …, 2022 - Taylor & Francis
Inflammation is a beneficial and physiological process, but there are a number of
inflammatory diseases which have detrimental effects on the body. In addition, the drugs …

Mitochondrial dysfunction and neurological disorders: a narrative review and treatment overview

EE Alshial, MI Abdulghaney, AHS Wadan… - Life Sciences, 2023 - Elsevier
Mitochondria play a vital role in the nervous system, as they are responsible for generating
energy in the form of ATP and regulating cellular processes such as calcium (Ca 2+) …

Mitochondrial fission and fusion: molecular mechanisms, biological functions, and related disorders

M Al Ojaimi, A Salah, AW El-Hattab - Membranes, 2022 - mdpi.com
Mitochondria are dynamic organelles that undergo fusion and fission. These active
processes occur continuously and simultaneously and are mediated by nuclear-DNA …

The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction

W Gong, L Lu, Y Zhou, J Liu, H Ma… - American Journal …, 2021 - journals.physiology.org
Stimulator of interferon genes (STING) is an important adaptor in cytosolic DNA-sensing
pathways. A recent study found that the deletion of STING ameliorated cisplatin-induced …

Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate Sepsis-Induced Acute Kidney Injury by Promoting Mitophagy of Renal Tubular Epithelial Cells via the …

J Guo, R Wang, D Liu - Frontiers in endocrinology, 2021 - frontiersin.org
Sepsis is a common risk factor for acute kidney injury (AKI). Bone marrow-derived
mesenchymal stem cells (BMSCs) bear multi-directional differentiation potential. This study …

Adipose‐derived stem cells regulate metabolic homeostasis and delay aging by promoting mitophagy

M Lv, S Zhang, B Jiang, S Cao, Y Dong… - The FASEB …, 2021 - Wiley Online Library
Tissues undergo a process of degeneration as the body ages. Mesenchymal stem cells
(MSCs) have been found to have major potential in delaying the aging process in tissues …

[HTML][HTML] Characteristics and regulation of mesenchymal stem cell plasticity by the microenvironment—Specific factors involved in the regulation of MSC plasticity

L Tan, X Liu, H Dou, Y Hou - Genes & Diseases, 2022 - Elsevier
Mesenchymal stem cells (MSCs), multipotent stromal cells, have attracted extensive
attention in the field of regenerative medicine and cell therapy due to the capacity of self …

Novel thermosensitive hydrogel promotes spinal cord repair by regulating mitochondrial function

Y Li, L Yang, F Hu, J Xu, J Ye, S Liu… - … Applied Materials & …, 2022 - ACS Publications
The repair of spinal cord injury (SCI) is still a tough clinical challenge and needs innovative
therapies. Mitochondrial function is significantly compromised after SCI and has emerged as …

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Regulate the Mitochondrial Metabolism via Transfer of miRNAs

C Loussouarn, YM Pers, C Bony, C Jorgensen… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are the most commonly tested adult progenitor cells in
regenerative medicine. They stimulate tissue repair primarily through the secretion of …

Mitochondria in Mesenchymal Stem Cells: Key to Fate Determination and Therapeutic Potential

Y Liu, L Wang, J Ai, K Li - Stem Cell Reviews and Reports, 2024 - Springer
Mesenchymal stem cells (MSCs) have become popular tool cells in the field of
transformation and regenerative medicine due to their function of cell rescue and cell …