Purified β‐glucans from the Shiitake mushroom ameliorates antibiotic‐resistant Klebsiella pneumoniae‐induced pulmonary sepsis

CH Masterson, EJ Murphy, H Gonzalez… - Letters in Applied …, 2020 - academic.oup.com
Bacterial infection remains the main cause of acute respiratory distress syndrome and is a
leading cause of death and disability in critically ill patients. Here we report on the use of …

Mesenchymal stem cells and tuberculosis: Clinical challenges and opportunities

X Zhang, Q Xie, Z Ye, Y Li, Z Che, M Huang… - Frontiers in …, 2021 - frontiersin.org
Tuberculosis (TB) is one of the communicable diseases caused by Mycobacterium
tuberculosis (Mtb) infection, affecting nearly one-third of the world's population. However …

Umbilical cord-derived CD362+ mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy

S Horie, C Masterson, J Brady, P Loftus… - Stem cell research & …, 2020 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) demonstrate considerable promise
for acute respiratory distress syndrome (ARDS) and sepsis. However, standard approaches …

[HTML][HTML] Review of the potential of mesenchymal stem cells for the treatment of infectious diseases

A Sharma, A Chakraborty… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
The therapeutic value of mesenchymal stem cells (MSCs) for the treatment of infectious
diseases and the repair of disease-induced tissue damage has been explored extensively …

Unveiling heterogeneity in MSCs: exploring marker-based strategies for defining MSC subpopulations

S Chen, B Liang, J Xu - Journal of Translational Medicine, 2024 - Springer
Mesenchymal stem/stromal cells (MSCs) represent a heterogeneous cell population
distributed throughout various tissues, demonstrating remarkable adaptability to …

Nebulised mesenchymal stem cell derived extracellular vesicles ameliorate E. coli induced pneumonia in a rodent model

H Gonzalez, S McCarthy, C Masterson… - Stem Cell Research & …, 2023 - Springer
Background Mesenchymal stem cell (MSC) derived extracellular vesicles (EVs) have been
proposed as an alternative to cell therapy, creating new possible delivery modalities such as …

[HTML][HTML] Umbilical cord-derived mesenchymal stem cells for COVID-19 patients with acute respiratory distress syndrome (ARDS)

G Lanzoni, E Linetsky, D Correa… - CellR4--repair …, 2020 - ncbi.nlm.nih.gov
The coronavirus SARS-CoV-2 is cause of a global pandemic of a pneumonia-like disease
termed Coronavirus Disease 2019 (COVID-19). COVID-19 presents a high mortality rate …

Single‐cell transcriptome profiling reveals molecular heterogeneity in human umbilical cord tissue and culture‐expanded mesenchymal stem cells

Q Wang, J Li, S Wang, Q Deng, K Wang… - The FEBS …, 2021 - Wiley Online Library
Human umbilical cord‐derived mesenchymal stem/stromal cells (UMSCs) demonstrate great
therapeutic potential in regenerative medicine. The use of UMSCs for clinical applications …

Mesenchymal stromal cell‐derived syndecan‐2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation

J Han, Y Shi, G Willis, J Imani, MY Kwon, G Li… - The FEBS …, 2022 - Wiley Online Library
Sepsis is a life‐threatening process related to a dysregulated host response to an
underlying infection, which results in organ dysfunction and poor outcomes. Therapeutic …

Mesenchymal stromal cells attenuate infection-induced acute respiratory distress syndrome in animal experiments: a meta-analysis

W Fengyun, Z LiXin, Q Xinhua, F Bin - Cell Transplantation, 2020 - journals.sagepub.com
Mesenchymal stromal cell (MSC) therapy is a potential therapy for treating acute lung injury
(ALI) or acute respiratory distress syndrome (ARDS), which was widely studied in the last …