Pneumonia and renal replacement therapy are risk factors for ceftazidime-avibactam treatment failures and resistance among patients with carbapenem-resistant …
RK Shields, MH Nguyen, L Chen… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Ceftazidime-avibactam was used to treat 77 patients with carbapenem-resistant
Enterobacteriaceae (CRE) infections at our center. Thirty-and 90-day survival rates were …
Enterobacteriaceae (CRE) infections at our center. Thirty-and 90-day survival rates were …
Evolution of hypervirulence in carbapenem-resistant Klebsiella pneumoniae in China: a multicentre, molecular epidemiological analysis
Abstract Objectives Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP)
have been increasingly reported in China. Here, a multicentre, longitudinal surveillance …
have been increasingly reported in China. Here, a multicentre, longitudinal surveillance …
OXA-48-Like β-Lactamases: global epidemiology, treatment options, and development pipeline
SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …
[HTML][HTML] Management of carbapenem-resistant Enterobacteriaceae infections
E Durante-Mangoni, R Andini, R Zampino - Clinical Microbiology and …, 2019 - Elsevier
Background Carbapenem resistance is defined as in vitro non-susceptibility to any
carbapenem and/or documented production of a carbapenemase. This feature has rapidly …
carbapenem and/or documented production of a carbapenemase. This feature has rapidly …
Effect of carbapenem resistance on outcomes of bloodstream infection caused by Enterobacteriaceae in low-income and middle-income countries (PANORAMA): a …
Background Low-income and middle-income countries (LMICs) are under-represented in
reports on the burden of antimicrobial resistance. We aimed to quantify the clinical effect of …
reports on the burden of antimicrobial resistance. We aimed to quantify the clinical effect of …
[HTML][HTML] Resistance to ceftazidime/avibactam in infections and colonisations by KPC-producing Enterobacterales: a systematic review of observational clinical studies
S Di Bella, DR Giacobbe, AE Maraolo, V Viaggi… - Journal of Global …, 2021 - Elsevier
ABSTRACT Ceftazidime/avibactam (CAZ-AVI), approved in 2015, is an important first-line
option for KPC-producing Enterobacterales (KPC-E). Although still uncommon, resistance to …
option for KPC-producing Enterobacterales (KPC-E). Although still uncommon, resistance to …
[HTML][HTML] Molecular Mechanisms, Epidemiology, and Clinical Importance of β-Lactam Resistance in Enterobacteriaceae
G De Angelis, P Del Giacomo, B Posteraro… - International journal of …, 2020 - mdpi.com
Despite being members of gut microbiota, Enterobacteriaceae are associated with many
severe infections such as bloodstream infections. The β-lactam drugs have been the …
severe infections such as bloodstream infections. The β-lactam drugs have been the …
[HTML][HTML] Carbapenem-resistant Acinetobacter baumannii: in pursuit of an effective treatment
Abstract Background Carbapenem-resistant Acinetobacter baumannii (CRAB) has gained
global notoriety as a critically important nosocomial pathogen. It mostly affects debilitated …
global notoriety as a critically important nosocomial pathogen. It mostly affects debilitated …
Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European …
Background Antimicrobial de-escalation (ADE) is a strategy of antimicrobial stewardship,
aiming at preventing the emergence of antimicrobial resistance (AMR) by decreasing the …
aiming at preventing the emergence of antimicrobial resistance (AMR) by decreasing the …
Multidrug-resistant Klebsiella pneumoniae: challenges for treatment, prevention and infection control
M Bassetti, E Righi, A Carnelutti… - Expert review of anti …, 2018 - Taylor & Francis
Introduction: Management of antimicrobial resistance in multi-drug-resistant-Klebsiella
pneumoniae (MDR-KP) is a major challenge for clinicians. The optimal treatment option for …
pneumoniae (MDR-KP) is a major challenge for clinicians. The optimal treatment option for …