During the last decades, the isolation of multidrug-resistant Gram-negative (MDR-GN)
bacteria has dramatically increased worldwide and has been associated with significant …

Combination therapy including colistin and a carbapenem has been found to be associated
with lower mortality in the treatment of bloodstream infections (BSI) due to KPC-producing …

The advancements in surgical techniques, immunosuppressive therapies, and infection
control and prophylaxis, along with significant changes in the policy of graft recruitment and …

With the current crisis related to the emergence of carbapenem-resistant Gram-negative
bacteria (CR-GNB), classical treatment approaches with so-called “old-fashion antibiotics” …

Abstract Purpose of Review Gram-negative resistance is a growing concern globally.
Enterobacterales, formerly Enterobacteriaceae, have developed resistance mechanisms to …

Klebsiella pneumoniae remains a major pathogen responsible for localized infections such
as cystitis and pneumonia, and disseminated infections that may result in severe sepsis and …

Abstract Purpose of Review The purpose of this review is to investigate the evolution and
epidemiology of Klebsiella pneumoniae carbapenemase (KPC)-producing organisms and …

Objectives CARB-ES-19 is a comprehensive, multicenter, nationwide study integrating
whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K …

The objective of this study was to investigate predisposing factors and outcomes of infective
endocarditis (IE) caused by non-HACEK Gram-negative bacilli (GNB) in a contemporary …

Abstract Background Carbapenemase-producing Klebsiella pneumoniae has become a
global priority, not least in low-and middle-income countries. Here, we report the emergence …