[HTML][HTML] Artificial intelligence in accelerating vaccine development-current and future perspectives
Tackling antimicrobial resistance requires the development of new drugs and vaccines.
Artificial intelligence (AI) assisted computational approaches offer an alternative to the …
Artificial intelligence (AI) assisted computational approaches offer an alternative to the …
Microparticles and nanoparticles-based approaches to improve oral treatment of Helicobacter pylori infection
JA Paes Dutra, S Gonçalves Carvalho… - Critical Reviews in …, 2023 - Taylor & Francis
Helicobacter pylori is a gram-negative, spiral-shaped, flagellated bacterium that colonizes
the stomach of half the world's population. Helicobacter pylori infection causes pathologies …
the stomach of half the world's population. Helicobacter pylori infection causes pathologies …
[HTML][HTML] Vaccine design from the ensemble of surface glycoprotein epitopes of SARS-CoV-2: an immunoinformatics approach
The present study aimed to work out a peptide-based multi-epitope vaccine against the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We predicted different B …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We predicted different B …
[HTML][HTML] Integrated core proteomics, subtractive proteomics, and immunoinformatics investigation to unveil a potential multi-epitope vaccine against schistosomiasis
Schistosomiasis is a parasitic infection that causes considerable morbidity and mortality in
the world. Infections of parasitic blood flukes, known as schistosomes, cause the disease …
the world. Infections of parasitic blood flukes, known as schistosomes, cause the disease …
[HTML][HTML] Designing a Multi-Epitope Vaccine against Chlamydia trachomatis by Employing Integrated Core Proteomics, Immuno-Informatics and In Silico Approaches
Simple Summary Chlamydia trachomatis is the most common cause of blindness, ectopic
pregnancy, and bacterial sexually transmitted infections. These diseases affect mostly young …
pregnancy, and bacterial sexually transmitted infections. These diseases affect mostly young …
Therapeutic target identification via differential genome analysis of antibiotic resistant Shigella sonnei and inhibitor evaluation against a selected drug target
Z Basharat, M Jahanzaib, N Rahman - Infection, Genetics and Evolution, 2021 - Elsevier
Shigella sonnei has been implicated in bloody diarrhea (accompanied by abdominal pain
and fever) and is an emerging pathogen of concern, especially in developing countries. The …
and fever) and is an emerging pathogen of concern, especially in developing countries. The …
Designing a multi-epitope vaccine against Chlamydia pneumoniae by integrating the core proteomics, subtractive proteomics and reverse vaccinology-based …
Chlamydia pneumoniae, a pneumonia causing specie belonging to chlamydia bacterium. C.
pneumonia is considered as a leading cause of pneumonia. Apart from that, C. pneumoniae …
pneumonia is considered as a leading cause of pneumonia. Apart from that, C. pneumoniae …
Differential analysis of Orientia tsutsugamushi genomes for therapeutic target identification and possible intervention through natural product inhibitor screening
Z Basharat, U Akhtar, K Khan, G Alotaibi, K Jalal… - Computers in Biology …, 2022 - Elsevier
Orientia tsutsugamushi (Ott) is a causative agent of scrub typhus, and one of the emerging
pathogens that could affect a large human population. It is one of the misdiagnosed and …
pathogens that could affect a large human population. It is one of the misdiagnosed and …
[HTML][HTML] Identification of Drug Targets and Their Inhibitors in Yersinia pestis Strain 91001 through Subtractive Genomics, Machine Learning, and MD Simulation …
Yersinia pestis, the causative agent of plague, is a Gram-negative bacterium. If the plague is
not properly treated it can cause rapid death of the host. Bubonic, pneumonic, and …
not properly treated it can cause rapid death of the host. Bubonic, pneumonic, and …
[HTML][HTML] Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant
The newly discovered SARS-CoV-2 Omicron variant B. 1.1. 529 is a Variant of Concern
(VOC) announced by the World Health Organization (WHO). It's becoming increasingly …
(VOC) announced by the World Health Organization (WHO). It's becoming increasingly …