Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer

CT Stump, K Roehle, N Manjarrez Orduno… - Open …, 2021 - royalsocietypublishing.org
Radiation has been a pillar of cancer therapy for decades. The effects of radiation on the anti-
tumour immune response are variable across studies and have not been explicitly defined in …

[PDF][PDF] Type 2 immunity is maintained during cancer-associated adipose tissue wasting

PJ Lenehan, A Cirella, AM Uchida… - Immunotherapy …, 2021 - academic.oup.com
Objectives: Cachexia is a systemic metabolic disorder characterized by loss of fat and
muscle mass, which disproportionately impacts patients with gastrointestinal malignancies …

Radiolabeled chemotherapeutics as a novel strategy for targeted cancer therapy: current insights and future perspectives

A Jain, T Das - Journal of Radioanalytical and Nuclear Chemistry, 2024 - Springer
The use of radiolabeled chemotherapeutics is an exciting prospect in the management of
cancer, as lethal cytotoxic radiation dose can be delivered to the cancerous lesions by using …

T cell immunity ameliorates COVID-19 disease severity and provides post-exposure prophylaxis after peptide-vaccination, in Syrian hamsters

E Somogyi, M Kremlitzka, Z Csiszovszki… - Frontiers in …, 2023 - frontiersin.org
Background The emergence of novel SARS-CoV-2 variants that resist neutralizing
antibodies drew the attention to cellular immunity and calls for the development of …

Glaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A …

C Schmelter, KN Fomo, A Brueck, N Perumal… - Biomolecules, 2023 - mdpi.com
Glaucoma is a complex, multifactorial optic neuropathy mainly characterized by the
progressive loss of retinal ganglion cells (RGCs) and their axons, resulting in a decline of …

[PDF][PDF] Response challenges to cancer immunotherapies

I Al-Janabi - Al-Rafidain Journal of Medical Sciences (ISSN 2789 …, 2022 - iasj.net
Humans have an exquisite immune system that enables them to not only identify and
eliminate foreign antigens but also their own cells if they go awry. Cancer cells, through …

Engineered Constitutive Promoter for Cell-Based Immunotherapy in Syngeneic Mouse Models

CKC Lam - 2023 - search.proquest.com
Living cells can be engineered into cell-based therapeutics by utilizing synthetic genetic
elements and protein effectors that reprogram cell activity to be able to treat diseases …

Introducing Immunotherapy Advances

T Elliott - Immunotherapy Advances, 2021 - academic.oup.com
There has never been a better time to launch a new journal to serve the field of
immunotherapy. In the treatment of cancer, autoimmune disease and allergy, we have …