Mild cognitive impairment (MCI) is common in people with chronic kidney disease (CKD),
and its prevalence increases with progressive loss of kidney function. MCI is characterized …

Background Anesthetized animal models are used extensively during neurophysiological
and behavioral studies despite systemic effects from anesthesia that undermine both …

Clinical evidence suggests that a mild traumatic brain injury occurring at a juvenile age
(jmTBI) may be sufficient to elicit pathophysiological modifications. However, clinical reports …

There is growing concern that repetitive subconcussive head impacts, independent of
concussion, alter brain structure and function, and may disproportionately affect the …

The brain pericyte is a unique and indispensable part of the blood-brain barrier (BBB), and
contributes to several pathological processes in traumatic brain injury (TBI). However, the …

Abusive head trauma in infants is a consequence of multiple episodes of abuse and results
in axonal injury, brain atrophy, and chronic cognitive deficits. Anesthetized 11-day-old rats …

The rat median nerve model is a well-established and frequently used model for peripheral
nerve injury and repair. The grasping test is the gold-standard to evaluate functional …

Introduction High-fat diet (HFD) consumption is known to trigger an inflammatory response
in the brain that prompts the dysregulation of energy balance, leads to insulin and leptin …

Introduction Allografts are the most common bone grafts for repairing osseous defects.
However, their use is associated with an increased risk for infections, donor disease …

Background Magnetic resonance imaging (MRI) of rodents combined with histology allows
to determine what mechanisms underlie functional and structural brain changes during …