The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …

Cytomegalovirus (CMV) infection is a major cause of morbidity and mortality after
hematopoietic stem cell transplantation. Significant progress has been made in the …

Cytomegalovirus (CMV) infection is a significant complication in hematopoietic cell
transplantation (HCT) recipients. Four antiviral drugs are used for preventing or treating …

Purpose The objective of this review was to summarize the recent literature describing the
current burden of disease due to herpesviruses in the antiviral and transplant era; describe …

Nucleoside analogues such as acyclovir and ganciclovir have been the mainstay of therapy
for alphaherpesviruses (herpes simplex virus (HSV) and varicella-zoster virus (VZV)) and …

Despite remarkable advances in the diagnostic and therapeutic modalities for its
management, cytomegalovirus (CMV) remains one of the most important pathogens …

Human cytomegalovirus (HCMV) infections are common and lead to lifelong infections. In
immunocompetent individuals, primary infections are mostly subclinical or they may be …

In the absence of effective vaccines to control herpesvirus infections, nucleosidic antiviral
drugs have been the mainstay of clinical treatment since their development in the late …

Though an important cause of morbidity and mortality in solid organ transplantation (SOT),
the long-term outcomes of cytomegalovirus (CMV) disease treatment have not been well …

Despite standard therapy, cytomegalovirus (CMV) disease recurs in a significant proportion
of organ transplant recipients. The kinetics of CMV load in response to therapy may allow …