Caffeic acid is a plant-derived compound that is classified as hydroxycinnamic acid which
contains both phenolic and acrylic functional groups. Caffeic acid has been greatly …

Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …

The most recent European guidelines and task force reports on hospital-acquired
pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Objective To identify research priorities in the management, epidemiology, outcome and
underlying causes of sepsis and septic shock. Design A consensus committee of 16 …

Objective: To provide an update to the “Surviving Sepsis Campaign Guidelines for
Management of Severe Sepsis and Septic Shock,” last published in 2008. Design: A …

The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …

Severe pneumonia is associated with high mortality (short and long term), as well as
pulmonary and extrapulmonary complications. Appropriate diagnosis and early initiation of …

The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …