Nanotechnological approaches in prostate cancer therapy: integration of engineering and biology
Nanocarriers have received special attention in biomedicine for the treatment of various
diseases, especially cancer, as one of the leading causes of death worldwide. Nanocarriers …
diseases, especially cancer, as one of the leading causes of death worldwide. Nanocarriers …
Comparison of anticancer drug toxicities: paradigm shift in adverse effect profile
D Basak, S Arrighi, Y Darwiche, S Deb - Life, 2021 - mdpi.com
The inception of cancer treatment with chemotherapeutics began in the 1940s with nitrogen
mustards that were initially employed as weapons in World War II. Since then, treatment …
mustards that were initially employed as weapons in World War II. Since then, treatment …
[HTML][HTML] Inhibition of phosphoglycerate dehydrogenase induces ferroptosis and overcomes enzalutamide resistance in castration-resistant prostate cancer cells
J Wang, L Zeng, N Wu, Y Liang, J Jin, M Fan… - Drug Resistance …, 2023 - Elsevier
Phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme in the first step of the
serine synthesis pathway (SSP), is overexpressed in multiple types of cancers. The …
serine synthesis pathway (SSP), is overexpressed in multiple types of cancers. The …
MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis
J Gan, S Liu, Y Zhang, L He, L Bai, R Liao… - … & molecular medicine, 2022 - nature.com
The functional role of microRNA-375 (miR-375) in the development of prostate cancer (PCa)
remains controversial. Previously, we found that plasma exosomal miR-375 is significantly …
remains controversial. Previously, we found that plasma exosomal miR-375 is significantly …
LncRNA PCBP1-AS1-mediated AR/AR-V7 deubiquitination enhances prostate cancer enzalutamide resistance
B Zhang, M Zhang, C Shen, G Liu, F Zhang, J Hou… - Cell Death & …, 2021 - nature.com
The refractory of castration-resistant prostate cancer (CRPC) is mainly reflected in drug
resistance. The current research on the resistance mechanism of CRPC is still in its infancy …
resistance. The current research on the resistance mechanism of CRPC is still in its infancy …
Chiral Selenium Nanotherapeutics Regulates Selenoproteins to Attenuate Glucocorticoid‐Induced Osteoporosis
Z Xiong, H Lin, H Li, B Zou, B Xie, Y Yu… - Advanced Functional …, 2023 - Wiley Online Library
Abstract Glucocorticoid (GC)‐induced osteoporosis (GIO) is a concurrent disease commonly
appeared in chronic inflammatory and autoimmune disease patients. Stereoselective …
appeared in chronic inflammatory and autoimmune disease patients. Stereoselective …
Non-coding RNA-based regulation of inflammation
Inflammation is a multifactorial process and various biological mechanisms and pathways
participate in its development. The presence of inflammation is involved in pathogenesis of …
participate in its development. The presence of inflammation is involved in pathogenesis of …
Non-coding RNAs in enzalutamide resistance of castration-resistant prostate cancer
K Gao, X Li, J Ni, B Wu, J Guo, R Zhang, G Wu - Cancer Letters, 2023 - Elsevier
Enzalutamide (Enz) is a next-generation androgen receptor (AR) antagonist used to treat
castration-resistant prostate cancer (CRPC). Unfortunately, the relapsing nature of CRPC …
castration-resistant prostate cancer (CRPC). Unfortunately, the relapsing nature of CRPC …
Role of exosomes in prostate cancer and male fertility
D Dey, S Ghosh, D Mirgh, SP Panda, NK Jha… - Drug Discovery …, 2023 - Elsevier
Prostate cancer (PCa) is the second most common and fifth most aggressive neoplasm
among men worldwide. In the last decade, extracellular vesicle (EV) research has decoded …
among men worldwide. In the last decade, extracellular vesicle (EV) research has decoded …
YAP antagonizes TEAD‐mediated AR signaling and prostate cancer growth
Hippo signaling restricts tumor growth by inhibiting the oncogenic potential of YAP/TAZ‐
TEAD transcriptional complex. Here, we uncover a context‐dependent tumor suppressor …
TEAD transcriptional complex. Here, we uncover a context‐dependent tumor suppressor …