Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022 - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Towards a deeper understanding of the vaginal microbiota

M France, M Alizadeh, S Brown, B Ma, J Ravel - Nature microbiology, 2022 - nature.com
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …

[HTML][HTML] Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health

WJY Chee, SY Chew, LTL Than - Microbial cell factories, 2020 - Springer
Human vagina is colonised by a diverse array of microorganisms that make up the normal
microbiota and mycobiota. Lactobacillus is the most frequently isolated microorganism from …

[HTML][HTML] The female vaginal microbiome in health and bacterial vaginosis

X Chen, Y Lu, T Chen, R Li - Frontiers in cellular and infection …, 2021 - frontiersin.org
The vaginal microbiome is an intricate and dynamic microecosystem that constantly
undergoes fluctuations during the female menstrual cycle and the woman's entire life. A …

[HTML][HTML] Bacterial vaginosis and its association with infertility, endometritis, and pelvic inflammatory disease

J Ravel, I Moreno, C Simón - American journal of obstetrics and …, 2021 - Elsevier
Bacterial vaginosis, pelvic inflammatory disease, and endometritis are infections of the
genital tract that can lead to many adverse health outcomes, including infertility. Bacterial …

The microbiome and gynaecological cancer development, prevention and therapy

P Łaniewski, ZE Ilhan, MM Herbst-Kralovetz - Nature Reviews Urology, 2020 - nature.com
The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …

[HTML][HTML] Randomized trial of lactin-V to prevent recurrence of bacterial vaginosis

CR Cohen, MR Wierzbicki, AL French… - … England Journal of …, 2020 - Mass Medical Soc
Background Bacterial vaginosis affects 15 to 50% of women of reproductive age, and
recurrence is common after treatment with an antibiotic agent. The high incidence of …

Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - Am Soc Microbiol
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

[HTML][HTML] Bacterial vaginosis and health-associated bacteria modulate the immunometabolic landscape in 3D model of human cervix

P Łaniewski, MM Herbst-Kralovetz - npj Biofilms and Microbiomes, 2021 - nature.com
Bacterial vaginosis (BV) is an enigmatic polymicrobial condition characterized by a
depletion of health-associated Lactobacillus and an overgrowth of anaerobes. Importantly …

[HTML][HTML] Bacterial vaginosis: drivers of recurrence and challenges and opportunities in partner treatment

LA Vodstrcil, CA Muzny, EL Plummer, JD Sobel… - BMC medicine, 2021 - Springer
Bacterial vaginosis (BV) is the most common vaginal dysbiosis to affect women globally, yet
an unacceptably high proportion of women experience BV recurrence within 6 months of …