High-voltage electrical pulses in oncology: irreversible electroporation, electrochemotherapy, gene electrotransfer, electrofusion, and electroimmunotherapy
B Geboers, HJ Scheffer, PM Graybill, AH Ruarus… - Radiology, 2020 - pubs.rsna.org
This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …
oncology to treat solid tumors with irreversible electroporation (IRE) and …
Electroporation-based technologies for medicine: principles, applications, and challenges
When high-amplitude, short-duration pulsed electric fields are applied to cells and tissues,
the permeability of the cell membranes and tissue is increased. This increase in permeability …
the permeability of the cell membranes and tissue is increased. This increase in permeability …
Selective modulation of intracellular effects of cells using pulsed electric fields
A system and method for selectively treating aberrant cells such as cancer cells through
administration of a train of electrical pulses is described. The pulse length and delay …
administration of a train of electrical pulses is described. The pulse length and delay …
Irreversible electroporation: background, theory, and review of recent developments in clinical oncology
KN Aycock, RV Davalos - Bioelectricity, 2019 - liebertpub.com
Irreversible electroporation (IRE) has established a clinical niche as an alternative to thermal
ablation for the eradication of unresectable tumors, particularly those near critical vascular …
ablation for the eradication of unresectable tumors, particularly those near critical vascular …
[HTML][HTML] Modeling of electric field distribution in tissues during electroporation
S Corovic, I Lackovic, P Sustaric, T Sustar… - Biomedical engineering …, 2013 - Springer
Background Electroporation based therapies and treatments (eg electrochemotherapy, gene
electrotransfer for gene therapy and DNA vaccination, tissue ablation with irreversible …
electrotransfer for gene therapy and DNA vaccination, tissue ablation with irreversible …
[HTML][HTML] Electroporation and immunotherapy—unleashing the abscopal effect
Simple Summary Electrochemotherapy and irreversible electroporation are primarily used
for treating patients with cutaneous and subcutaneous tumors and pancreatic cancer …
for treating patients with cutaneous and subcutaneous tumors and pancreatic cancer …
[HTML][HTML] The effects of irreversible electroporation (IRE) on nerves
W Li, Q Fan, Z Ji, X Qiu, Z Li - PloS one, 2011 - journals.plos.org
Background If a critical nerve is circumferentially involved with tumor, radical surgery
intended to cure the cancer must sacrifice the nerve. Loss of critical nerves may lead to …
intended to cure the cancer must sacrifice the nerve. Loss of critical nerves may lead to …
Nonthermal irreversible electroporation: fundamentals, applications, and challenges
A Golberg, ML Yarmush - IEEE Transactions on biomedical …, 2013 - ieeexplore.ieee.org
Tissue ablation is an essential procedure for the treatment of many diseases. In the last
decade, a nonthermal tissue ablation using intensive pulsed electric fields, called …
decade, a nonthermal tissue ablation using intensive pulsed electric fields, called …
Treatment planning for electroporation-based therapies
2011-04-27 Assigned to VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
reassignment VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. ASSIGNMENT OF …
reassignment VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. ASSIGNMENT OF …
Initial assessment of safety and clinical feasibility of irreversible electroporation in the focal treatment of prostate cancer
Background: To evaluate the safety and clinical feasibility of focal irreversible
electroporation (IRE) of the prostate. Methods: We assessed the toxicity profile and …
electroporation (IRE) of the prostate. Methods: We assessed the toxicity profile and …