Glucocorticoid receptor activities in the zebrafish model: A review

A Dinarello, G Licciardello, CM Fontana… - Journal of …, 2020 - joe.bioscientifica.com
Glucocorticoids (GCs) are steroid hormones that contribute to the regulation of many
physiological processes, such as inflammation, metabolism and stress response, mainly …

Interrenal development and function in zebrafish

I Bacila, VT Cunliffe, NP Krone - Molecular and Cellular Endocrinology, 2021 - Elsevier
In this article we aim to provide an overview of the zebrafish interrenal development and
function, as well as a review of its contribution to basic and translational research. A search …

Trpv4-mediated apoptosis of Leydig cells induced by high temperature regulates sperm development and motility in zebrafish

Y Yamamoto, D Hishikawa, F Ono - Communications Biology, 2024 - nature.com
Exposure of testes to high-temperature environment results in defective spermatogenesis.
Zebrafish exposed to high temperature exhibited apoptosis not only in germ cells but also in …

[HTML][HTML] Steroidogenic electron-transfer factors and their diseases

WL Miller - Annals of Pediatric Endocrinology & Metabolism, 2021 - ncbi.nlm.nih.gov
Most steroidogenesis disorders are caused by mutations in genes encoding the
steroidogenic enzymes, but work in the past 20 years has identified related disorders …

Cortisol Directly Stimulates Spermatogonial Differentiation, Meiosis, and Spermiogenesis in Zebrafish (Danio rerio) Testicular Explants

A Tovo-Neto, ERM Martinez, AG Melo, LB Doretto… - Biomolecules, 2020 - mdpi.com
Cortisol is the major endocrine factor mediating the inhibitory effects of stress on vertebrate
reproduction. It is well known that cortisol affects reproduction by interacting with the …

11β-Hydroxylase loss disrupts steroidogenesis and reproductive function in zebrafish

JA Oakes, L Barnard, KH Storbeck… - Journal of …, 2020 - joe.bioscientifica.com
The roles of androgens in male reproductive development and function in zebrafish are
poorly understood. To investigate this topic, we employed CRISPR/Cas9 to generate …

Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells

D Crespo, LHC Assis, YT Zhang, D Safian… - Communications …, 2021 - nature.com
Pituitary hormones can use local signaling molecules to regulate target tissue functions. In
adult zebrafish testes, follicle-stimulating hormone (Fsh) strongly increases the production of …

Embryonic Exposure to the Benzotriazole Ultraviolet Stabilizer 2‐(2H‐benzotriazol‐2‐yl)‐4‐methylphenol Decreases Fertility of Adult Zebrafish (Danio rerio)

Y Raza, E Mertens, L Zink, Z Lu… - Environmental …, 2024 - Wiley Online Library
Benzotriazole ultraviolet stabilizers (BUVSs) are emerging contaminants of concern. They
are added to a variety of products, including building materials, personal care products …

Multi species analyses reveal testicular T3 metabolism and signalling as a target of environmental pesticides

V Nittoli, M Colella, A Porciello, C Reale, L Roberto… - Cells, 2021 - mdpi.com
Thyroid hormones (THs) regulate many biological processes in vertebrates, including
reproduction. Testicular somatic and germ cells are equipped with the arrays of enzymes …

Elevated glucocorticoid alters the developmental dynamics of hypothalamic neurogenesis in zebrafish

H Eachus, MK Choi, A Tochwin, J Kaspareit… - Communications …, 2024 - nature.com
Exposure to excess glucocorticoid (GC) during early development is implicated in adult
dysfunctions. Reduced adult hippocampal neurogenesis is a well-known consequence of …