The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …

Eosinophils are bone marrow-derived granulocytes that, under homeostatic conditions,
account for as much as 1-3% of peripheral blood leukocytes. During inflammation …

Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a vasculitis
characterized by eosinophilic inflammation. Benralizumab, a monoclonal antibody against …

Since its global invasion in 2019, COVID-19 has affected several aspects of patients' lives
and posed a significant impact on the health care system. Several patient populations were …

Aim The International Severe Asthma Registry (ISAR; http://isaregistries. org/) uses
standardised variables to enable multi-country and adequately powered research in severe …

Siglecs (sialic acid-binding immunoglobulin-like lectins) are a family of vertebrate glycan-
binding cell-surface proteins. The majority mediate cellular inhibitory activity once engaged …

Gender differences in the functionality of the immune system have been attributed, in part, to
direct and indirect effects of sex steroids, especially estrogens, on immune cell repertoire …

Background In mice models, eosinophils have been divided into different subpopulations
with distinct phenotypes and functions, based on CD62L and CD101 patterns of membrane …

Eosinophils are innate immune cells typically associated with allergic and parasitic
diseases. However, in recent years, eosinophils have also been ascribed a role in keeping …

Eosinophils are a class of granulocytes with pleiotropic functions in homeostasis and
various human diseases. Nevertheless, they are absent from conventional single-cell RNA …