Serotonin is a naturally occurring vasoactive substance that has diverse cardio-
physiological effects. These effects can be explained by the existence of serotonin receptor …

Serotonin, or 5‐hydroxytryptamine, is a naturally‐occurring vasoactive substance found
primarily in the brain, enterochromaffin tissue, and blood platelets. It has diffuse …

Study objective—To determine whether ketanserin, an antagonist at the serotonin receptor,
prevents important vascular events such as death, myocardial infarction, major stroke, and …

Publisher Summary This chapter gives an overview of class III electrophysiological agents,
which are considered a new generation of antiarrhythmic therapy. Arrhythmias can range …

Hypertensive disorders of pregnancy are the leading cause of maternal and perinatal
mortality and morbidity in developing and developed countries. The etiology of …

High-performance liquid chromatography with electrochemical detection (HPLC-ED) is a
popular method for measuring biogenic amines, owing to its simplicity, versatility, sensitivity …

Several lines of evidence suggest that serotonin (5-HT) has a regulatory role in
cardiovascular function from embryogenesis through adulthood. However, the reported …

The colocalisation of neuropeptide Y (NPY)-and 5-hydroxytryptamine (5-HT)-
immunoreactivities in intracardiac neurones in dissociated cultures from the atria and …

Background and purpose: Ketanserin, a selective 5‐HT receptor antagonist, prolongs the QT
interval of ECG in patients. The purpose of the present study was to determine whether …

Ketanserin (KT), an antihypertensive agent, has been shown to prolong action potential
duration (APD) and QT interval and to induce torsade de pointes in some patients. We …