Nitric oxide (NO) is of fundamental importance in regulating immune, cardiovascular,
reproductive, neuromuscular, and nervous system function. It is rapidly synthesized and …

Tinnitus, the perception of sound with no external auditory stimulus, is a complex,
multifaceted, and potentially devastating disorder. Despite recent advances in our …

Experiments in rodent animal models help to reveal the characteristics and underlying
mechanisms of pathologies related to hearing loss such as tinnitus or hyperacusis …

Noise-induced hearing deficits are important health problems in the industrialized world. As
the underlying physiological dysfunctions are not well understood, research in suitable …

Hearing loss is well known to cause plastic changes in the central auditory system and
pathological changes such as tinnitus and hyperacusis. Impairment of inner ear functions is …

Exposure to nontraumatic noise in vivo drives long-lasting changes in auditory nerve
synapses, which may influence hearing, but the induction mechanisms are not known. We …

The anti-inflammatory drug salicylate induces tinnitus in animals and man. Salicylate
reduces cochlear output but causes hyperactivity in higher auditory centres, including the …

Guinea pigs (Cavia porcellus) are a commonly used species in biomedical research. As
social creatures, compatible guinea pigs should be housed together unless scientific …

T‐stellate cells in the ventral cochlear nucleus (VCN) are known to have local axon
collaterals that terminate in the vicinity of their dendrites and cell bodies within the same …

Abstract Background and Aim: Tinnitus is a common disorder of the auditory system with a
rich history dating back to ancient times. This review aims to provide a historical perspective …