Extracellular vesicles in cardiovascular disease: biological functions and therapeutic implications

C Han, J Yang, J Sun, G Qin - Pharmacology & therapeutics, 2022 - Elsevier
Extracellular vesicles (EVs), including exosomes and microvesicles, are lipid bilayer
particles naturally released from the cell. While exosomes are formed as intraluminal …

Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Strontium ions protect hearts against myocardial ischemia/reperfusion injury

M Xing, Y Jiang, W Bi, L Gao, YL Zhou, SL Rao… - Science …, 2021 - science.org
Timely restoration of blood supply following myocardial infarction is critical to save the
infarcted myocardium, while reperfusion would cause additional damage. Strontium ions …

[HTML][HTML] Exosomes and exosomal cargos: a promising world for ventricular remodeling following myocardial infarction

J Fang, Y Zhang, D Chen, Y Zheng… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Exosomes are a pluripotent group of extracellular nanovesicles secreted by all cells that
mediate intercellular communications. The effective information within exosomes is primarily …

Dissolving microneedles for long-term storage and transdermal delivery of extracellular vesicles

VD Bui, S Son, W Xavier, JM Jung, J Lee, S Shin… - Biomaterials, 2022 - Elsevier
Extracellular vesicles (EVs) have shown great potential in disease diagnosis and treatment;
however, their clinical applications remain challenging due to their unsatisfactory long-term …

[HTML][HTML] Stem cell-derived extracellular vesicles as new tools in regenerative medicine-immunomodulatory role and future perspectives

E Karnas, P Dudek, EK Zuba-Surma - Frontiers in immunology, 2023 - frontiersin.org
In the last few decades, the practical use of stem cells (SCs) in the clinic has attracted
significant attention in the regenerative medicine due to the ability of these cells to proliferate …

A biodegradable, flexible photonic patch for in vivo phototherapy

K Deng, Y Tang, Y Xiao, D Zhong, H Zhang… - Nature …, 2023 - nature.com
Diagnostic and therapeutic illumination on internal organs and tissues with high
controllability and adaptability in terms of spectrum, area, depth, and intensity remains a …

Intercellular communication in the heart: therapeutic opportunities for cardiac ischemia

T Martins-Marques, DJ Hausenloy, JPG Sluijter… - Trends in Molecular …, 2021 - cell.com
The maintenance of tissue, organ, and organism homeostasis relies on an intricate network
of players and mechanisms that assist in the different forms of cell–cell communication …

Engineering bacterial membrane nanovesicles for improved therapies in infectious diseases and cancer

J Gao, Y Su, Z Wang - Advanced drug delivery reviews, 2022 - Elsevier
Research on bacterial membrane vesicles (BMVs) is an emerging topic, and the goal is to
address whether BMVs can bring translational tools to improve current therapies. In this …

Exosome-based cell-free therapy in regenerative medicine for myocardial repair

KH Haider, M Najimi - Handbook of stem cell therapy, 2022 - Springer
Exosomes in cardiovascular theranostics are gaining popularity due to their immense
diagnostic and therapeutic potential generally ascribed to their specific payload and …